:: Volume 4, Issue 3 (1-2013) ::
Caspian J Intern Med 2013, 4(3): 739-742 Back to browse issues page
Chronic myeloid leukemia following colon cancer treatment: A case report and literature review
Mohsen Vakili-Sadeghi , Mohammadhasan Omranpour
Abstract:   (4730 Views)
Background: Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer.
Case Presentation: A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. Then he developed BCR-ABL positive CML. With Imatinib 400 mg/day, he achieved hematologic response but died because of progressive colon cancer.
Conclusion: This article emphasizes that there is a possibility for etiologic correlation between CML and chemotherapeutic agents in solid cancers.
Keywords: Chemotherapy, Chronic myelogenous leukemia, Colon cancer
Full-Text [PDF 179 kb]   (1067 Downloads)    
Type of Study: Original Article | Subject: Infectious Diseases
Received: 2014/01/17 | Accepted: 2014/01/17 | Published: 2014/01/17

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Volume 4, Issue 3 (1-2013) Back to browse issues page