[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 12، شماره 2 - ( 12-1399 ) ::
جلد 12 شماره 2 صفحات 217-222 برگشت به فهرست نسخه ها
Comparison of the Effect of Oral Pregabalin with Intravenous Ketamine on Reducing Pain after Abdominal Hysterectomy: A Randomized Double-blind Clinical Trial Study
چکیده:   (188 مشاهده)
Background: The aim of this study was to compare the analgesic effects of pregabalin and ketamine on reducing pain after abdominal hysterectomy.
Methods: In this double-blind clinical trial, one hundred forty ASA I and II patients of age range 30-60 years scheduled for abdominal hysterectomy undergoing general anesthesia in 2018, were randomly divided into 4 equal groups. Pregabalin group received 300 mg oral pregabalin, ketamine group received 0.3 mg/kg of intravenous ketamine, and pregabalin- ketamine group received the combination of the two-above medication, and placebo group received the placebo and saline. Patients were evaluated for pain intensity according to the visual analogue scale (VAS) at 2, 4, 6, 12, 18, and 24 hours after surgery. Also, the need for analgesic drugs and the frequency of repetitions were also recorded. Statistical analysis was performed using STATA, Version 14. A p- value less than 0.05 was considered statistically significant.
Results: In the pregabalin and pregabalin-ketamine groups, pain in the first 6 hours after the end of operation was significantly less than the other two groups (p<0.05), but there was no significant difference between the 4 groups at 18 and 24 hours after surgery. The need for analgesic medications in the pregabalin group was lower than in other groups (p<0.05).
Conclusion: The results of this study show that the administration of oral pregabalin with and without intravenous ketamine before abdominal hysterectomy can decrease postoperative pain and reduce the need for analgesia.
متن کامل [PDF 284 kb]   (64 دریافت)    
نوع مطالعه: Original Article | موضوع مقاله: Anesthesiology
دریافت: 1398/11/23 | پذیرش: 1400/1/10 | انتشار: 1400/1/10
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA



XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ghadami N, Sarshivi F, Barzanji A, Nouri B, Mohammadi Z. Comparison of the Effect of Oral Pregabalin with Intravenous Ketamine on Reducing Pain after Abdominal Hysterectomy: A Randomized Double-blind Clinical Trial Study. Caspian J Intern Med. 2021; 12 (2) :217-222
URL: http://caspjim.com/article-1-2214-fa.html

Comparison of the Effect of Oral Pregabalin with Intravenous Ketamine on Reducing Pain after Abdominal Hysterectomy: A Randomized Double-blind Clinical Trial Study. 1. 1399; 12 (2) :217-222

URL: http://caspjim.com/article-1-2214-fa.html



دوره 12، شماره 2 - ( 12-1399 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4287