[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
بخش‌های اصلی
صفحه اصلی::
اطلاعات نشریه::
برای نویسندگان::
آرشیو مجله و مقالات::
برای داوران::
ثبت نام و اشتراک::
تماس با ما::
تسهیلات پایگاه::
بایگانی مقالات زیر چاپ::
::
جستجو در پایگاه

جستجوی پیشرفته
..
دریافت اطلاعات پایگاه
نشانی پست الکترونیک خود را برای دریافت اطلاعات و اخبار پایگاه، در کادر زیر وارد کنید.
..
:: دوره 6، شماره 4 - ( 7-1394 ) ::
جلد 6 شماره 4 صفحات 212-209 برگشت به فهرست نسخه ها
Relationship between hepatitis B DNA Viral load in the liver and it's histology in patient with chronic hepatitis B
چکیده:   (8862 مشاهده)

Background: Serial measurement of  hepatitis B virus (HBV) DNA levels in the liver and its relation with liver damage and serum HBV DNA levels are guide to begin and/or end a treatment course. This study evaluated the relationship between liver hepatitis B DNA viral load with liver histology in patients with chronic hepatitis B (HBV).

Methods:  Thirty patients with chronic anti-Hbe positive hepatitis B, with liver enzymes &ge 2 times of the upper limit of normal and positive HBV DNA of any amount were entered in the study. They underwent percutaneous liver biopsy. Liver and serum viral load were determined using real time polymerase chain reaction (RT-PCR) method. Liver function tests and liver histology for all cases were recorded. The amount of viral load in the liver and histological grading and staging were recorded. Data were collected and analyzed.

Results: The mean age of the patients was 32.8±10 years and 24 (80%) patients were males. Ten (33.3%) patients had HBV viral load levels less than 20000 IU/mL. There was a significant correlation between liver viral load levels with staging or grading of liver damage.

Conclusion: The results of the present study showed a strong correlation between liver viral load and liver damage in patients with chronic hepatitis B.

 

متن کامل [PDF 300 kb]   (3163 دریافت)    
نوع مطالعه: Original Article | موضوع مقاله: Infectious Diseases
دریافت: 1393/6/3 | پذیرش: 1394/3/19 | انتشار: 1394/6/17
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA


XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Biazar T, Yahyapour Y, Hasanjani Roushan M R, Rajabnia R, Sadegi M, Ranaei M et al . Relationship between hepatitis B DNA Viral load in the liver and it's histology in patient with chronic hepatitis B. Caspian J Intern Med 2015; 6 (4) :209-212
URL: http://caspjim.com/article-1-388-fa.html

Relationship between hepatitis B DNA Viral load in the liver and it's histology in patient with chronic hepatitis B. 1. 1394; 6 (4) :209-212

URL: http://caspjim.com/article-1-388-fa.html



بازنشر اطلاعات
Creative Commons License این مقاله تحت شرایط Creative Commons Attribution-NonCommercial 4.0 International License قابل بازنشر است.
دوره 6، شماره 4 - ( 7-1394 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.06 seconds with 37 queries by YEKTAWEB 4645