Case series of rhinocerebral mucormycosis occurring in diabetic patients
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Rasoul Mohammadi , Mohsen Meidani , Kamyar Mostafavizadeh , Bijan Iraj , Pooria Hamedani , Mohammad Amin Sayedain , Mojgan Mokhtari |
Department of Infectious Diseases, Al-Zahra hospital, Isfahan University of Medical Sciences, Isfahan, Iran , meidani@med.mui.ac.ir |
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Abstract: (8979 Views) |
Background: Rhinocerebral mucormycosis is a fatal infection typically affecting diabetic or immunosuppressed patients. In most cases, infection is caused by inhalation of fungal spores. Mortality rate of patients is very high (40-85%).
Case Presentation: In this study, three diabetic patients with rhinocerebral mucormycosis were presented. The etiologic agents of mucormycosis in two patients were isolated and identified by sequence analysis and data were registered in Gene bank database.
Conclusion: In patients with mucormeosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.
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Keywords: Rhinocerebral mucormycosis, Diabetes Mellitus, Iran |
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Full-Text [PDF 437 kb]
(2898 Downloads)
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Type of Study: Case Series |
Subject:
Infectious Diseases Received: 2015/03/9 | Accepted: 2015/07/11 | Published: 2015/09/13
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