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:: دوره 9، شماره 1 - ( 10-1396 ) ::
جلد 9 شماره 1 صفحات 100-103 برگشت به فهرست نسخه ها
Sarcoidosis and spondyloarthritis: A coincidence or common etiopathogenesis?
چکیده:   (2747 مشاهده)
Background: Sarcoidosis is a multisystem granulomatous disease. Co-existence with spondyloarthritis (SA) has been more described as an adverse effect of anti-TNF α therapy than an association. We report herein a case of a typical sarcoidosis confirmed by histological proofs and an advanced SA with a bamboo column.
Case Presentation: A 48-years-old woman presented with inflammatory back pain for 5 years and ankle swelling for 1 year. On physical examination, she had an exaggerated dorsal kyphosis and disappearance of lumbar lordosis with limitation in motion of the cervical and lumbar spine. Laboratory tests did not show an inflammatory syndrome or hypercalcemia. Plain radiographies of the spine and pelvic revealed a triple ray appearance with sacroiliitis grade 4. Chest radiography and CT confirmed the presence of bilateral hilar lymph nodes and parenchymal nodes. Bronchoscopy and biopsies were performed showing non-calcified granulomatous reaction without cell necrosis. The diagnosis of SA was performed based on 9 points of Amor criteria associated with pulmonary sarcoidosis. She was treated with 15 mg per week of methotrexate and 1mg/kg/day of prednisone for pulmonary disease with good outcomes.
Conclusions: Sarcoidosis may be associated to SA besides paradoxical drug effect. The same physio pathological pathways mediate by TNF α are arguments for association than hazardous coincidence

متن کامل [PDF 254 kb]   (414 دریافت)    
نوع مطالعه: case report | موضوع مقاله: Reumatology
دریافت: ۱۳۹۵/۶/۱۲ | پذیرش: ۱۳۹۵/۱۲/۲۳ | انتشار: ۱۳۹۶/۸/۸
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Hamdi W, Miladi S, Kaffel D, Zouch I, Kchir M M. Sarcoidosis and spondyloarthritis: A coincidence or common etiopathogenesis?. Caspian J Intern Med. 2018; 9 (1) :100-103
URL: http://caspjim.com/article-1-860-fa.html

Sarcoidosis and spondyloarthritis: A coincidence or common etiopathogenesis?. 1. 1396; 9 (1) :100-103

URL: http://caspjim.com/article-1-860-fa.html



دوره 9، شماره 1 - ( 10-1396 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
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