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:: Volume 9, Issue 2 (1-2018) ::
Caspian J Intern Med 2018, 9(2): 201-203 Back to browse issues page
Inflammatory myopathies in a patient with Darier's disease, a possible association
Kaveh Gharaeinejad , Hojat Eftekhari , Rana Rafiei , Abbas Darjani , Narges Alizadeh
Department of Dermatology, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran , dr.he.der@gmail.com
Abstract:   (6982 Views)
Background: Darier disease (DD) is an autosomal dominant genetic disorder which develops from a mutation in the ATP2A2 gene. Inflammatory myopathies (IM) are the largest group of potentially treatable myopathies. In this case, we report development of IM in a patient with DD for the second time in the literature.
Case presentation: The patient is a 59-year-old female, a known case of  DD, who developed proximal muscle weakness 2 weeks prior to admission. Elevated muscle-enzymes, as well as typical electromyographic and radiologic confirmed the diagnosis of IM.
Conclusions: Abnormalities in intracellular calcium homeostasis may explain the association between DM and DD, therefore it is noteworthy to keep this association in mind and conduct more research regarding this issue

Keywords: Darier Disease, Inflammatory myopathy, dermatomyositis, poly myositis
Full-Text [PDF 343 kb]   (961 Downloads)    
Type of Study: case report | Subject: Dermathology
Received: 2016/11/2 | Accepted: 2017/05/13 | Published: 2018/01/9
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Gharaeinejad K, Eftekhari H, rafiei R, Darjani A, Alizadeh N. Inflammatory myopathies in a patient with Darier's disease, a possible association. Caspian J Intern Med 2018; 9 (2) :201-203
URL: http://caspjim.com/article-1-906-en.html


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Volume 9, Issue 2 (1-2018) Back to browse issues page
Caspian Journal of Internal Medicine
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