%0 Journal Article %A Yazdani, Mohammad %A Ghaemian, Nasser %A Khafri, Soraya %A Oliaei, Farshid %T Can the kidney volume help to differentiate the types of rejection before biopsy? %J Caspian Journal of Internal Medicine %V 10 %N 1 %U http://caspjim.com/article-1-1358-en.html %R 10.22088/cjim.10.1.11 %D 2019 %K Keywords : Kidney transplantation, kidney volume, AMR, CMR, Ultrasonography, %X Background: The aim of this study was to use the volume of the graft as an adjunct tool for better decision making. Methods: Kidney transplanted patients with acute azotemia and documented volume and finally a biopsy were enrolled in this study‌. Graft volumes between rejected patients (antibody-mediated rejection {AMR} and cell - mediated rejection {CMR}) and ‌non rejected but azotemic patients were compared. Results: A total of 76 patients were enrolled in this study ‌(45 case and 31 control‌). 53.3% of the case group were‌ (AMR)‌ and 46.7% belonged to ‌(CMR). There was no difference between kidney volume according to age or sex. But the case group had a significantly bigger volume than controls (253.09 cm3 and 186.45 cm3; p< 0.001). In addition, there was a significant difference between the volumes of AMR kidneys with CMR and controls ‌(286.24+66.70‌, 224.08+76.79 and 186.95+39.92; P=0.003 and p<0.001, respectively), but not between CMR and controls ‌(P=0.067). A cutoff point of 200 cm3 was determined as rejection with sensitivity and specificity of 70% and a cutoff point of 250 cm3 could be used as AMR cut off with sensitivity of 76% and specificity of 70%. Conclusion: There was a significant difference in volume between rejection and control group and between AMR and CMR. So, kidney volume determination is an easy and valuable tool to help the clinician to have a more rapid and better decision making. %> http://caspjim.com/article-1-1358-en.pdf %P 11-15 %& 11 %! Kidney volume help to differentiate the types of rejection before biopsy %9 Original Article %L A-10-158-3 %+ Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran %G eng %@ 2008-6164 %[ 2019