%0 Journal Article %A Saburi, Ehsan %A Saburi, Amin %A Ghanei, Mostafa %T Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside %J Caspian Journal of Internal Medicine %V 8 %N 4 %U http://caspjim.com/article-1-847-en.html %R 10.22088/cjim.8.4.228 %D 2017 %K Cancer, Immunotherapy, Macrophage activating factor, GC-MAF, Vitamin D., %X Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms. %> http://caspjim.com/article-1-847-en.pdf %P 228-238 %& 228 %! Gc-MAF Therapy in Cancer %9 Review Article %L A-10-605-1 %+ Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran %G eng %@ 2008-6164 %[ 2017