AU - Saburi, Ehsan AU - Saburi, Amin AU - Ghanei, Mostafa TI - Promising role for Gc-MAF in cancer immunotherapy: from bench to bedside PT - JOURNAL ARTICLE TA - babol-caspjim JN - babol-caspjim VO - 8 VI - 4 IP - 4 4099 - http://caspjim.com/article-1-847-en.html 4100 - http://caspjim.com/article-1-847-en.pdf SO - babol-caspjim 4 ABĀ  - Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics medications can also enhance immune-cell activity against tumors. Such medications show great potential in cancer immunotherapy using natural human mechanisms against neoplasms. CP - IRAN IN - Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran LG - eng PB - babol-caspjim PG - 228 PT - Review Article YR - 2017