AU - Yousefghahari, Behnaz AU - Alhooei, Saman AU - Soleimani- amiri, Mohammad Jafar AU - Guran, Ardeshir TI - Comparison of sensitivity and specificity of anti-CCP and anti-MCV antibodies in an Iranian cohort of patients with rheumatoid arthritis PT - JOURNAL ARTICLE TA - babol-caspjim JN - babol-caspjim VO - 4 VI - 3 IP - 3 4099 - http://caspjim.com/article-1-208-en.html 4100 - http://caspjim.com/article-1-208-en.pdf SO - babol-caspjim 3 ABĀ  - Background: Anti-CCP is a test commonly used for the diagnosis of rheumatoid arthritis. The aim of this study was to determine the diagnostic values of ACCP compared to anti-MCV in rheumatoid arthritis patients in north of Iran. Methods: The serum samples of 150 RA patients and 75 controls, with the mean age of 49.6+11.8 and 48.8+12 years respectively, were tested using the commercially available ELISA kits for ACCP and anti-MCV. Sensitivity, Specificity were determined and Roc curve were used for comparison between these two groups.Results: The sensitivity of ACCP versus anti-MCV was 85% and 81%, respectively. Specificity was 96% and 95%, respectively. In the RA patients, ACCP was positive in 127 (84.7%) and anti MCV in 121 (80.7%) cases. In the control group, these parameters were positive in 3 (4%) and 4 (5.3%) (p CP - IRAN IN - LG - eng PB - babol-caspjim PG - 702 PT - Original Article YR - 2013