RT - Journal Article T1 - Transcranial doppler sonography diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine JF - babol-caspjim YR - 2011 JO - babol-caspjim VO - 2 IS - 1 UR - http://caspjim.com/article-1-97-en.html SP - 178 EP - 182 K1 - Transcranial Doppler sonography (TCD) K1 - Migraine with aura K1 - Photo stimulation AB - Background: An imbalance of the cerebrovascular response during functional activation of the brain has been postulated as a factor in the pathophysiology of migraine. The purpose of this study was to determine the transcranial doppler sonography (TDS) diagnostic value for the cerebral flow velocity changes in the interictal phase of classic migraine. Methods: This study was carried out on 46 patients (23 cases and 23 controls). We used Doppler instrument via trans-temporal window and detected middle cerebral artery, anterior cerebral artery and posterior cerebral artery by 2 MHz probe. The flow velocity in the posterior cerebral artery before, during and immediately after stimulation was recorded. Stimulation was done using a flickering light in 100 seconds. Results: At the baseline, the middle cerebral artery had more peak systolic velocity in migraineurs than the control group. Although peak systolic velocity changes in the mid-photic period is not statistically significant. On the other hand, post-photic peak systolic velocity increased significantly. The diagnostic accuracy of the peak systolic volume (PSV) changes in the posterior cerebral artery (PCA) for the migraine was 72.3%. Conclusion: This stimulation we found altered cerebral vasomotor reactivity in the interictal phase in migraineurs with visual aura. This seemed to be an unavoidable hindrance for the wider implementation of functional TCD in diagnostic work up of migraine patients. LA eng UL http://caspjim.com/article-1-97-en.html M3 ER -