Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1396
10
1
gregorian
2018
1
1
9
2
online
1
fulltext
en
Is 99m Tc-methylene diphosphonate bone scintigraphy a sensitive method for detecting bone lesions in multiple myeloma?
Hematology
Hematology
Original Article
Original Article
<span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background:</em></strong></span> Bone lesion in multiple myeloma (MM) is most commonly presented as a lytic lesion in this disease. Determination of extent of bone lesions in MM is necessary to follow-up the patients. Whole body bone scan with 99m, Tc-methylene diphosphonate (MDP) has a lower sensitivity than other modalities.<br>
<span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em></span> From the patients with MM admitted to Ayatollah Rouhani Hospital of Babol-Iran from 2009 to 2015, who had undergone whole body bone scan during diagnostic process, were entered into the study. Findings of bone scan were compared with MRI.<br>
<span style="color:#0000FF;"><strong><em>Results:</em></strong></span> Of the 19 patients, sixteen (84.2%) of them had positive finding in bone scan, fifteen (78.9%) had MRI of the spine. While of the thirteen patients who had positive finding in MRI, seven (53.8%) had more positive finding in thorcolumbosacral MRI than in bone scan.<br>
<span style="color:#0000FF;"><strong><em>Conclusions:</em></strong></span> 99m-Tc MDP bone scan is a sensitive but insufficient method for detecting bone lesions in MM.</span></span><br>
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Tc-99m methylene diphosphonate, bone lesion, multiple myeloma
140
143
http://caspjim.com/browse.php?a_code=A-10-117-1&slc_lang=en&sid=1
Mohsen
Vakili-sadeghi
mvakili89@gmail.com
100319475328460011949
100319475328460011949
Yes
Babol university of medical sciences2. Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Sadegh
Sedaghat
sadeghsedaghat@yahoo.com
100319475328460011950
100319475328460011950
No
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran