Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1397
10
1
gregorian
2019
1
1
10
1
online
1
fulltext
en
Comparison of pathologic characteristics of breast cancer in younger and older women
Oncology
Oncology
Original Article
Original Article
<span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em></span> Breast cancer is the most common invasive cancer with high mortality in women all around the world. The present evidence shows that younger patients have poor survival. Thus, the aim of this study was to compare the pathologic characteristics of breast cancer in women younger than 40 years compared with older.<br>
<span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em></span> This is a cross-sectional study which contains 681 patients with a confirmed diagnosis of breast cancer, who referred to Babolsar Shahid Rajaei Hospital as a referral cancer therapeutic center in the North of Iran. The data included age, residence area, occupation, location, histopathologic characteristics of the tumor, TNM classification and staging.<br>
<span style="color:#0000FF;"><strong><em>Results</em></strong><em>:</em> </span>The mean age (SD) of patients was 49.7 (11.9) years, of which 19.5% were under 40. Ductal carcinoma was the most common histopathologic type (90.0%) but patients at a younger age had a higher incidence of lobular and other rare carcinoma compared to the older ones (P=0.04). The younger had a greater tumor size (P=0.01), lymphatic node involvement (P=0.04) and higher staging (P=0.004). The younger age was not associated with positive estrogen/progesterone receptors.<br>
<span style="color:#0000FF;"><strong><em>Conclusion</em></strong><em>:</em> </span>These findings indicated more aggressive tumor characteristics and serious breast cancer in women less than 40 years compared with older ones.</span></span>
Breast cancer, younger women, tumor characteristics, TNM classification
42
47
http://caspjim.com/browse.php?a_code=A-10-133-4&slc_lang=en&sid=1
Reza
Yazdani Charati
rzyzdn@yahoo.com
100319475328460014976
100319475328460014976
No
Student Research Committee, Babol University of Medical Sciences, Babol, Iran
Karimollah
Hajian-Tilaki
drhajian@yahoo.com
100319475328460014977
100319475328460014977
No
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Majid
Sharbatdaran
sharbatdaran@yahoo.com
100319475328460014978
100319475328460014978
Yes
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran