Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1391
10
1
gregorian
2013
1
1
4
3
online
1
fulltext
en
Psoriasis in hyper IgE syndrome – a case report
Infectious Diseases
Infectious Diseases
Original Article
Original Article
Background: Hyper IgE syndrome (HIES) is a rare primary immune deficiency, described as Job`s syndrome characterized by increased serum levels of IgE, eczema, recurrent cutaneous and pulmonary infections. In this paper, we presented a case of Hyper IgE syndrome.<br>Case Presentation: A 16-year-old Iranian boy presented with a one year history of skin lesions in knees and elbows was diagnosed of psoriasis disease. He had a history of recurrent infections including otitis media, pneumonia, diarrea and skin infection. Laboratory results showed increased level of total IgE and normal in other immunoglobulin. Histologic finding showed hyperkeratosis, parakeratosis of acanthotic epidermis with regular elongation of rete ridges diagnose psoriasis disorder.<br>Conclusion: In conclusion, this is the first case of hyper IgE patient with psoriasis disorder. We addressed the important laboratory findings and actual theories explaining possible association between hyper IgE immunoglobulinemia and psoriasis disorder.<br>
Hyper IgE syndrome, Psoriasis, Immune deficiency
735
738
http://caspjim.com/browse.php?a_code=A-10-62-153&slc_lang=en&sid=1
Javad
Ghaffari
1003194753284600840
1003194753284600840
Yes
Saeed
Abedian- Kenari
1003194753284600841
1003194753284600841
No
Maryam
Ghasemi
1003194753284600842
1003194753284600842
No
Farzad
Gohardehi
1003194753284600843
1003194753284600843
No