Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1393
6
1
gregorian
2014
9
1
5
4
online
1
fulltext
en
Does vitamin D status correlate with clinical and biochemical features of polycystic ovary syndrome in high school girls?
Internal
Internal
Original Article
Original Article
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><b><i><span style="color: blue">Abstract</span></i></b></span></span></p>
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"> <b><i><span style="color: blue">Background: </span></i></b>Prevalence of polycystic ovary syndrome (PCOs) is increasing particularly among the female adolescents and young women. It has been hypothesized that disturbance in calcium and vitamin-D metabolism may affect the symptoms of this syndrome. This study was designed to investigate the relationship between vitamin-D and calcium with metabolic parameters and other characteristics of the PCOs.</span></span></p>
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><b><i><span style="color: blue">Methods:</span></i></b> The study included 192 Iranian girls (16-20 years old), of whom 104 had PCOs and 88 were non-PCOs controls. Serum 25(OH) D and calcium level was measured. Anthropometric components, endocrine, metabolic components and insulin resistance were determined in PCOs subjects.</span></span></p>
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"> <b><i><span style="color: blue">Results:</span></i></b> Mean 25 (OH) D was significantly lower in cases (9.7±4.8) than controls (12.3±11.9) but calcium level did not differ between the two groups (9.3<span dir="rtl" lang="AR-SA">±</span>0.3 vs 9.4<span dir="rtl" lang="AR-SA">±</span>0.4). No significant correlations were found between 25(OH) D levels and lipid profile, FBS, fasting insulin endocrine parameters such as testosterone, free testosterone, FSH, LH, and prolactin. </span></span></p>
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"> <b><i><span style="color: blue">Conclusion: </span></i></b>Although hypovitamionos D was common is PCOs but did not correlate with clinical features or complications of obesity and insulin resistance PCO like severity of syndrome between vitamin-D deficiency and its severity with some features and complications of PCOs including obesity, insulin resistance.</span></span></p>
<p align="left"><span style="font-size:14px;"><span style="font-family:Times New Roman;"> </span></span></p>
Keywords: Polycystic ovary syndrome, Vitamin-D, Calcium, Younger girls.
202
208
http://caspjim.com/browse.php?a_code=A-10-62-198&slc_lang=en&sid=1
Reza
Ghadimi
100319475328460034249
100319475328460034249
No
Sedighe
Esmaeilzadeh
sesmael@yahoo.com
100319475328460034250
100319475328460034250
Yes
Marmar
Firoozpour
100319475328460034251
100319475328460034251
No
Asal
Ahmadi
100319475328460034252
100319475328460034252
No