Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1395
4
1
gregorian
2016
7
1
7
3
online
1
fulltext
en
Determinants of pain in patients with symptomatic knee osteoarthritis
Reumatology
Reumatology
Review Article
Review Article
<p style="margin: 0cm 0cm 0pt 161.6pt; text-indent: 0cm;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Background: </span></i></b><span style="font-size: 10pt;"><font color="#000000">Several factors are associated with the development or exacerbation of pain in knee osteoarthritis (KOA). In this study, we reviewed this context based on relevant studies.</font></span></font></p>
<div style="margin: 0cm 0cm 0pt 161.6pt; text-indent: 0cm;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Methods:</span></i></b><span style="font-size: 10pt;"><font color="#000000"> Recent published studies which have addressed the relationship between pain and KOA were summarized.</font></span></font></div>
<p style="margin: 0cm 0cm 0pt 161.6pt; text-indent: 0cm;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Results:</span></i></b><span style="font-size: 10pt;"><font color="#000000"> Correlates of the clinical, demographic features, laboratory tests and abnormalities on radiographic as well as magnetic resonance imaging (MRI) with the knee pain have been discussed. The results indicated that many factors such as synovitis, synovial effusion, obesity, as well as structural lesions determined by MRI or radiographic examination, serum cytokines, inflammatory markers are determinants of pain in KOA. </font></span></font></p>
<p style="margin: 0cm 0cm 0pt 161.6pt; text-indent: 0cm;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Conclusion:</span></i></b><span style="color: rgb(153, 51, 0); font-size: 10pt;"> </span><span style="font-size: 10pt;"><font color="#000000">This context requires further investigations for identification of additional factors which initiate pain in asymptomatic KOA</font></span></font></p>
Knee osteoarthritis, Pain, Determinants, Synovitis, C-reactive protein, Structural lesions
153
161
http://caspjim.com/browse.php?a_code=A-10-263-6&slc_lang=en&sid=1
Behzad
Heidari
heidaribeh@yahoo.com
10031947532846005946
10031947532846005946
No
Mobility Impairment Research Center, the Clinical Research Development Unit of Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
Karimollah
Hajian-Tilaki
mojy_rad@yahoo.com
10031947532846005947
10031947532846005947
No
Department of Social Medicine, Department of Statistics, Babol University of Medical Sciences, Babol, Iran
Mansour
Babaei
babaeim47@yahoo.com
10031947532846005948
10031947532846005948
Yes
Department of Internal medicine, Ayatollah Rouhani Hospital Division of Rheumatology, Babol University of Medical Sciences, Babol, Iran