en Internal Internal Original Article Original Article <p style="text-indent: 0cm; margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Background: </span></i></b><span style="font-size: 10pt;"><font color="#000000">Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly.</font></span></font></p> <p style="text-indent: 0cm; margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Methods:</span></i></b><span style="font-size: 10pt;"><font color="#000000"> In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and<b> </b>taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not<span style="background: white;"> take it.</span></font></span></font></p> <p style="text-indent: 0cm; margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Results:</span></i></b><span style="font-size: 10pt;"><font color="#000000"> A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92).</font></span></font></p> <p style="text-indent: 0cm; margin-top: 0cm; margin-right: 0cm; margin-bottom: 0pt;"><font face="Times New Roman"><b><i><span style="color: blue; font-size: 10pt;">Conclusion: </span></i></b><span style="font-size: 10pt;"><font color="#000000">Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly.</font></span></font></p> Aspirin, Elderly, Hematuria, Prevalence 278 282 http://caspjim.com/browse.php?a_code=A-10-570-1&slc_lang=en&sid=1 Emadouddin Moudi emadmoudi@gmail.com 10031947532846006638 10031947532846006638 No Department of Urology, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran. Seyed-Reza Hosseini bcrdc90@yahoo.com 10031947532846006639 10031947532846006639 No Department of Community Medicine, Social Determinants of Health (SDH) Research Center, Babol University of Medical Sciences, Babol, Iran. Ali Bijani alibijani@yahoo.com 10031947532846006640 10031947532846006640 Yes Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran