Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Toxoplasmosis in Iran: A guide for general physicians working in the Iranian health network setting: A systematic review
233
241
EN
Seyedmohammad
Alavi
Health Research Institute, Infections and Tropical Diseases Research Center, Jundishapur University of Medical Sciences,Ahvaz, Iran
alavi.seyedmohammad@yahoo.com
N
Leila
Alavi
Food and Drug Deputy, Jundishapur University of Medical Sciences,Ahvaz, Iran
leila.alavi 87@yahoo.com
Y
Background: Human toxoplasmosis is an important zoonotic infection worldwide which is caused by the intracellular parasite Toxoplasma gondii (T.gondii). The aim of this study was to review briefly the general aspects of toxoplasma infection in in Iranian health system network.
Methods: We searched published toxoplasmosis related articles in English databases including Science Direct, Pub Med, Scopus, Google Scholar, Magiran, Iran Medex, Iran Doc and Scientific Information Database (SID) for toxoplasmosis.
Results: Out of 1267 articles from the English and Persian databases search, 40 articles were suitable with our research objectives and so were selected for the study. It is estimated that at least a third of the world human population is infected with T.gondii, suggesting it as one of the most common parasitic infections through the world. Maternal infection during pregnancy may affect dangerous outcome for the fetus, or even cause intrauterine death. Reactivation of a previous infection in immunocompromised patient such as drug induced, AIDS and organ transplantation can cause life-threating central nervous system infection. Ocular toxoplasmosis is one of the most important causes of blindness, especially in individuals with a deficient immune system.
Conclusion: According to the increasing burden of toxoplasmosis on human health, the findings of this study highlight the appropriate preventive measures, diagnosis, and management of this disease.
Toxoplasma infection, T. gondii, Epidemiology, Health center, Iran
http://caspjim.com/article-1-428-en.html
http://caspjim.com/article-1-428-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Assessment of transient elastography (FibroScan) for diagnosis of fibrosis in non-alcoholic fatty liver disease: A systematic review and meta-analysis
242
252
EN
Seyyedabbas
Hashemi
Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran
amamali110@gmail.com
Y
Seyyedmoayed
Alavian
N
Mohammad
Gholami-Fesharaki
Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
N
Background: Transient elastography (TE) is a new modality for the diagnosis of liver fibrosis caused by various etiologies. This study was conducted to determine the accuracy of TE in detecting the different stages of liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients.
Methods: MEDLINE/PubMed, Embase, Ovid, Cochrane Library, American College of Physicians (ACP) Journal Club, Google Scholar, Database of Abstracts of Reviews of Effects, and Web of Science that evaluated the liver stiffness by means of TE and liver biopsy were enrolled in this systematic review and meta-analysis. Published articles were extracted from 2002 to March 2015.
Results: A total of 7 articles from 114 papers were included which consisted of 698 patients. The results indicated that when F ≥3, the outcomes were 93.7% (95% confidence interval (CI): 92-95.5), 91.1% (95% CI: 89-93.2), 82.4% (95% CI: 79.9-84.9), and 95.9% (95% CI: 94.4-97.4) for sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV), respectively. With fibrosis stage ≥4, it has reached the sensitivity of 96.2 % (95% CI: 94.5-97.8), a specificity of 92.2% (95% CI: 89.9-94.6), a PPV of 5.5% (95% CI: 51.2-59.8) and NPV of 98.5% (95% CI: 97.4-99.5).
Conclusion: We concluded that as the pathological fibrosis increases, the sensitivity, specificity and NPV of TE in the diagnosis of fibrosis improves in NAFLD patients. TE can be considered as a unique alternative instead of liver biopsy in NAFLD patients and it has an important role in the exclusion of liver cirrhosis. More studies are required to confirm the results.
Transient elastography, Fibro scan, Fibrosis, Non-alcoholic fatty liver disease
http://caspjim.com/article-1-720-en.html
http://caspjim.com/article-1-720-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Benefits from the correction of vitamin D deficiency in patients with pulmonary hypertension
253
259
EN
Ahmad
Mirdamadi
Islamic Azad University, Najafabad branch, Isfahan, Iran
drsamirdamadi@yahoo.com
N
Pouya
Moshkdar
Islamic Azad University, Najafabad branch, Isfahan, Iran
pooya.moshkdar@gmail.com
Y
Background: Vitamin D (Vit D) is linked to various conditions including musculoskeletal, metabolic and cardiopulmonary diseases. However, it is not clear whether correction of vit D deficiency exerts any beneficial effect in patients with pulmonary hypertension.
Methods: This study was a prospective uncontrolled longitudinal study. Patients with pulmonary hypertension and vit D deficiency were enrolled into this study. All patients in addition to standard treatment for pulmonary hypertension received cholecalciferol at a dose of 50,000 IU weekly plus calcicare (at a dose of 200 mg magnesium + 8 mg zinc + 400 IU vit D) daily for 3 months. Serum level of 25-hydroxy vit D, serum level of pro-brain natriuretic peptide, six minute walk test (6MWT), peak and mean pulmonary artery pressure, right ventricular size and function, ejection fraction (EF) and New York Heart Association (NYHA) functional class were measured at baseline and after 3 months of treatment.
Results: Twenty-two patients with pulmonary hypertension and vit D deficiency were enrolled into the study. At endpoint, the serum vit D level increased significantly to 54.8 ng/ml, the mean of baseline distance of 6MWT increased significantly to 81.6 m and the RV size significantly improved. The mean pulmonary artery pressure also improved after the intervention, but their changes did not reach to statistically significant levels.
Conclusion: Vit D replacement therapy in patients with pulmonary arterial hypertension and vit D deficiency results in significant improvement of right ventricular size and 6 MWT. Moreover, mean pulmonary artery pressure improves nonsignificantly. This issue requires further studies with long-term follow-up period.
Vitamin D deficiency, pulmonary hypertension, Replacement therapy
http://caspjim.com/article-1-716-en.html
http://caspjim.com/article-1-716-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
The HPLC assay of concentration of azithromycin from two different manufacturers in gingival crevicular fluid (GCF)
260
266
EN
Mahmoud
Khosravi Samani
Department of Periodontology, Babol University of medical sciences, Babol, Iran
samani_dr@yahoo.com
N
Khashayar
Dehshiri
Department of Periodontology, Babol University of medical sciences, Babol, Iran
drdehshiry@yahoo.com
N
Sohrab
Kazemi
2. Neurosciences Research Center, Department of Pharmacology, Babol University of medical sciences, Babol, Iran
kazemi.msm@gmail.com
N
Mohamadreza
Shiran
3. Department of Pharmacology, Mazandaran University of medical science, Sari, Iran
mohamadreza.shiran@yahoo.com
N
Ali Akbar
Moghadamnia
2. Neurosciences Research Center, Department of Pharmacology, Babol University of medical sciences, Babol, Iran
moghadamnia@gmail.com
Y
Background: Azithromycin (AZM) is used in periodontal infections. The present study compared gingival crevicular fluid concentration of azithromycin of two pharmaceutical companies through the HPLC method.
Methods: Two groups (n=15) of healthy volunteers participated in this study. The first group received an imported azithromycin (ImAZM) tablet (250 mg, PO) and the second group received an azithromycin tablet (250 mg PO) manufactured by an Iranian pharmaceutical company (IrAZM). Intrasulcular paper points (#30) were used in inter-proximal areas of molars and canines to collect gingival crevicular fluid samples at 6, 12, 36, 84 and 156 hours after drug administration.
Results: The maximum concentration of AZM in gingival crevicular fluid was detected in each group 36 hour after administration. The concentration levels for the participants receiving ImAZM and IrAZM were 14.38±5.75 and 12.64±3.53 ng/mL, respectively. The pharmacokinetic (PK) modeling data showed half-life of AZM was 107.47 hr & 91.42 hr while the clearance was 113.02 hr &119.0 hr for the group receiving ImAZM and IrAZM, respectively. No significant differences were observed in other PK parameters, areas under the concentration time curves for the groups were almost identical.
Conclusion: According to the results, there were no significant differences between the PK parameters of ImAZM and IrAZM products. It may be concluded that different doses of AZM have relatively similar PK parameters among the healthy participants.
Azithromycin, Pharmacokinetics, HPLC, Gingival crevicular fluid
http://caspjim.com/article-1-722-en.html
http://caspjim.com/article-1-722-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Comparison of levofloxacin versus clarithromycin efficacy in the eradication of Helicobacter pylori infection
267
271
EN
Aliakbar
Hajiaghamohammadi
Department of Internal Medicine,Velayat Clinical Research Development Unit, Qazvin University of Medical Sciences, Qazvin, Iran
ahmohammadi@qums.ac.ir
N
Ali
Bastani
Department of Internal Medicine,Velayat Clinical Research Development Unit, Qazvin University of Medical Sciences, Qazvin, Iran
dr_a_b76@yahoo.com
N
Arash
Miroliaee
Department of Internal Medicine,Velayat Clinical Research Development Unit, Qazvin University of Medical Sciences, Qazvin, Iran
arash_mir53@yahoo.com
N
Sonia
Oveisi
Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
soveisi@razi.tums.ac.ir
N
Saeed
Safarnezhad
Department of Internal Medicine,Velayat Clinical Research Development Unit, Qazvin University of Medical Sciences, Qazvin, Iran
Saeed_safarnezhad@yahoo.com
Y
Background: Helicobacter pylori (H.pylori) infection causes multiple upper gastrointestinal diseases but optimal therapeutic regimen which can eradicate infection in all the cases has not yet been defined. This study was designed to evaluate the efficacy of triple levofloxacin-based versus clarithromycin-based therapy.
Methods: In this open-label randomized clinical trial study 120 patients who had esophagogastroduodenoscopy (EGD) with positive rapid urease test (RUT) were enrolled and divided into 2 groups. Case group was treated with levofloxacin (500 mg daily) plus amoxicillin (1 gr twice a day) plus omeprazole (20 mg daily) for 2 weeks. Control group was treated with clarithromycin (500 mg twice a day) plus omeprazole (20 mg daily) for 2 weeks. After the main course of treatment, they received maintenance treatment with omeprazole for 4 weeks. Stool antigen test was performed on them after two weeks of not having any medicine.
Results: H.pylori eradication (intention to treat analysis) was successful in 75% of case group and 51.7% of control group showing a significant difference (P=0.008). H.p infection eradication (per-protocol analysis) was successful in 80.4% in case group and 57.4%% in control group showing significant difference (P=0.009). Drugs adverse effects causing discontinuation treatment were seen in 5% of case group and 3.3% of control group which have not shown a significant difference between the two groups (P=0.648).
Conclusion: Triple therapy with levofloxacin-based regimen has better efficacy than clarithromycin-based regimen and as safe as it is.
Helicobacter pylori, Dyspepsia, Peptic ulcer, Rapid urease test, Stool antigen
http://caspjim.com/article-1-751-en.html
http://caspjim.com/article-1-751-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Serum alpha–actinin antibody status in systemic lupus erythematosus and its potential in the diagnosis of lupus nephritis
272
277
FA
Mansour
Babaei
Department of Rheumatology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
babaeim47@yahoo.com
N
Zahra
Rezaieyazdi
Rheumatic Disease Research Center,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
rezaieyazdi-z@mums.ac.ir.
N
Nayereh
Saadati
Rheumatic Disease Research Center,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Saadatin@mums.ac.ir
Y
Massoud
Saghafi
Rheumatic Disease Research Center,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
saghafim@mums.ac.ir
N
Maryam
Sahebari
Rheumatic Disease Research Center,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
sahebarim@mums.ac.ir
N
Bahram
Naghibzadeh
Rheumatic Disease Research Center,School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
naghibzadehb@mums.ac.ir
N
Habibollah
Esmaily
Center for Health Sciences Research, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
esmailyh@mums.ac.ir
N
Background: In lupus nephritis (LN), deposition of pathogenic autoantibodies in the glomeruli is mediated via cross-reactivity with alpha-actinin. Association of serum alpha-actinin antibody (AαA) with LN has been shown in a few studies but the results are controversial.
Methods: Eighty patients into entered the study. The diagnosis of SLE was confirmed according to the American College of Rheumatology criteria and LN was diagnosed by proteinuria ≥ 500 mg/24 hour and kidney biopsy. Serum AαA was measured with ELISA method. Receiver operating characteristics curve (ROC) analysis was applied to determine an optimal cutoff value for AαA to discriminate patients with and without LN at the highest sensitivity and specificity. The association of AαA with LN was determined by logistic regression analysis with calculation of odds ratio (OR).
Results: Serum AαA was significantly lower in LN as compared with SLE patients without LN (P=0.001). Serum AαA at cutoff levels ≤ 59.5 pg/ml discriminated the two groups with sensitivity, specificity, positive predictive values of 60%. 90% and 85.7%, respectively. Serum AαA level ≤ 59.5 pg/ml was significantly associated with LN (OR=13.5, P=0.001) and the OR increased to 25.2 (P=0.003) after adjustment for age, sex, C3, C4, anti-ds-DNA, SLEDAI.
Conclusion: This study indicates that serum AαA decreases in LN and serum level ≤ 59.5 pg/ml is SLE and is predictive of nephritis.
Systemic lupus erythematous, Nephritis, Anti-alpha-actinicn antibody, Diagnosis
http://caspjim.com/article-1-793-en.html
http://caspjim.com/article-1-793-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Higher rate of microscopic hematuria in elderly patients who take regular doses of aspirin: Result from AHAP Study
278
282
EN
Emadouddin
Moudi
Department of Urology, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran.
emadmoudi@gmail.com
N
Seyed-Reza
Hosseini
Department of Community Medicine, Social Determinants of Health (SDH) Research Center, Babol University of Medical Sciences, Babol, Iran.
bcrdc90@yahoo.com
N
Ali
Bijani
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
alibijani@yahoo.com
Y
Background: Aspirin is the most widely used drug in medicine for cardiovascular and as recently for its role in cancer prevention. Although the risk of bleeding events increased following regular use of aspirin, little is known about the association of aspirin and hematuria. The present study aimed to evaluate the association of regular aspirin use and microscopic hematuria in elderly.
Methods: In this study, we have extracted the data of elderly people who participated in Amirkola Health and Aging Project (AHAP) and taking regular doses of aspirin. The prevalence of microscopic hematuria was compared between the elderly who took aspirin regularly and those who did not take it.
Results: A total of 1243 individuals (54.22% males, 45.78% females) were entered in to the study. Two hundred and eighty-four (23%) elderly took regular doses of aspirin. Microscopic hematuria was seen in 305 (24.54%) elderly. The prevalence of microscopic hematuria was 27.27% in regular users of aspirin and 23.72% in non-users of aspirin (P=0.126). The prevalence of microscopic hematuria was significantly higher among the regular users of aspirin compared to non-users in multiple logistic regression analysis (P=0.035, OR=1.40, 95%CI: 1.02-1.92).
Conclusion: Taking regular doses of aspirin was accompanied with higher rate of microscopic hematuria in the elderly.
Aspirin, Elderly, Hematuria, Prevalence
http://caspjim.com/article-1-805-en.html
http://caspjim.com/article-1-805-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Both immune hormone IL-10 and parathormone tend to increase in serum of old osteoporotic people independently of 1, 25 dihydroxy vitamin D3
283
289
EN
Mohamad
Teimorian
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol,Iran.
teimorianm@gmail.com
N
Zeinab
Jafarian
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol,Iran.
teimorianm@gmail.com
N
Seyed-Reza
Hosseyni
Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol,Iran.
hosseinirezaseyed@gmail.com
N
Mahsa
Rahmani
Immunology Department, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
teimorianm@gmail.com
N
Mojgan
Bagherzadeh
Immunology Department, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
mojan73@yahoo.com
N
Azin
Aghmajidi
Immunology Department, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
teimorianm@gmail.com
N
Ali
Bijani
Non-Communicable Pediatrics Diseases Research Center, Health Research institute, Babol University of Medical Sciences, Babol, Iran.
alibijani@yahoo.com
N
Hajighorban
Nooreddini
Departent of Radiology, Faculty of Medicine, Babol University of Medical Sciences, Babol,Iran
teimorianm@gmail.com
N
Amrollah
Mostafazadeh
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
amrolah65@yahoo.com
Y
Background: In this study, we determined the serum levels of IL-17A and IL-10 in context with 1, 2 dihydroxy vitamin D3, parathormone and Ca2+/Pi ions to investigate their pathological or protective roles respectively in bone metabolism.
Methods: The bone mineral density (BMD) was determined for 1203 participants using energy X-ray absorptiometry. Subjects with a history of diseases and using bone metabolism medications were excluded and finally serum IL-10 was measured in 82 osteoporotic and 74 healthy individuals (mean age ±SD of 71.04±6.9 and 68.58±6.9 respectively). Also, the serum level of IL-17A was assessed in 42 osteoporotic and 39 non-osteoporotic subjects (mean age±SD of 69.40±6.7 and 70.77±7.1, respectively). Serum levels of 1, 25-dihydroxyvitamin D3, Ca2+/Pi ions and parathormone were extracted from AHAP cohort data bank.
Results: IL-17A was detectable in 7.42(16.67%) osteoporotic subjects and 3.39(7.69%) normal subjects. Surprisingly, patient subjects exhibited a higher level of serum IL-10 than normal subjects (P=0.023). We found that the serum parathormone levels tend to increase in patient group (P=0.003) in comparison to normal control with no correlation with Il-10 levels. There was no significant difference between the two groups in the serum levels of 1, 25-dihydroxyvitamin D3, Ca2+and Pi ions.
Conclusion: In reaction to chronic inflammation old osteoporotic patients independent of 1, 25 dihydroxy vitamin D3 may produce a higher level of IL-10 to dampen production of inflammatory cytokines including IL-17A which in turn leads to speeding up parathormone production ultimately reaching a new homeostasis status in bone metabolism with normal serum Ca2+ /Pi ions.
Osteoporosis, IL-10, IL-17A, Parathormone, 1, 25dihydroxy vitamin D3, Elderly
http://caspjim.com/article-1-586-en.html
http://caspjim.com/article-1-586-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Comparison of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate in axillary acanthosis nigricans: A case series of patients in a before-after trial
290
293
EN
Amirhoshang
Ehsani
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
ehsanih@sina.tums.ac.ir
N
Pedram
Noormohammadpour
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
normohamad@razi.tums.ac.ir
N
Azadeh
Goodarzi
Department of Dermatology, Rasul Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran.
azadeh_goodarzi1984@yahoo.com
N
Mostafa
Mirshams-Shahshahani
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
mirshams-m@yahoo.com
N
Seyyed-Pardis
Hejazi
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
pardis.hegazi@gmail.com
N
Elham-Sadat
Hosseini
Tehran University of Medical Sciences (TUMS), Tehran, Iran
elham.s.hosseimi@yahoo.com
N
Arghavan
Azizpour
Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
a63a@yahoo.com
Y
Background: Acanthosis nigricans (AN) is a brown to black, velvety hyperpigmentation of the skin that usually involves cutaneous folds. Treatment of AN is important regarding cosmetic reasons and various therapeutic modalities have been used for these purposes. The goal of this study was to compare the effectiveness of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate for treatment of axillary-AN.
Methods: Fifteen patients with bilateral axillary-AN were studied in Razi Hospital, Tehran, Iran. Diagnosis was confirmed by two independent dermatologists. Each side skin lesion was randomly allocated to either topical mixed cream of tretinoin 0.05%- ammonium lactate 12% or long-pulsed alexandrite laser. Duration of treatment was 14 weeks. At endpoint, the mean percent reduction from baseline in pigmentation area was compared between the two groups.
Results: The study population consisted of 15 patients, three males and 12, females. The mean age of patients was 28.5±4.9 years. The mean percent reduction was 18.3±10.6%, in tretinoin/ammonium lactate group and 25.7±11.8% in laser group (P=0.004).
Conclusion: These findings indicate that the application of alexandrite laser is a relative effective method for treatment of axillary-AN. However, this issue requires further studies with prolonged follow-up period.
Acanthosis nigricans, Long-pulsed alexadrite laser, Tretinoin, Ammonium Lactate
http://caspjim.com/article-1-314-en.html
http://caspjim.com/article-1-314-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Implantable cardioverter-defibrillator in a patient with dextrocardia situs inversus
294
296
FA
Mehrdad
Saravi
Cardiology department, Babol University of Medical Sciences, Babol, Iran.
Y
Rozita
Jalalian
Cardiology department of Mazandaran University of Medical Sciences, Sari, Iran.
N
Mohammadtaghi
Hedayati
Cardiology department, Babol University of Medical Sciences, Babol, Iran.
N
Background: Dextrocardia is a congenital anomaly, which may have coexistent coronary artery disease (CAD), arrhythmias and conventional indications for device therapy. However, the implantation of transvenous leads can be technically challenging and the approach needs to be tailored to the patient's individual anatomy.
Case presentation: A 54-year-old male with dextrocardia situs inversus and ischemic left ventricular dysfunction developed ventricular tachycardia and fibrillation. Therefore, left- sided approach, dual chamber implantable cardioverter-defibrillator (ICD) was applied using a conventional method and standard equipment after complete evaluation of cardiac anatomy and vascular assessment.
Conclusion: Electrical device implantation in patients with dextrocardia is possible after obtaining complete information about anatomy and/or coexisting congenital abnormalities, which helps in obtaining appropriate implantation approach.
Dextrocardia, Situs inversus, Pacemaker, Implantable cardioverter-defibrillator (ICD), Multislice computed tomography
http://caspjim.com/article-1-874-en.html
http://caspjim.com/article-1-874-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Subclavian artery-esophageal fistula after placement of a self-expanding metal stent in a patient with esophagogastric anastomosis stenosis
297
299
EN
Mohammadreza
Seyyedmajidi
Golestan Research Center of Gastroenterology and Hepatology-GRCGH, Golestan University of Medical Sciences, Gorgan, Iran
mrsmajidi55@yahoo.com
N
Maryam
Tavassoli
Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
tavassoli1220@gmail.com
N
Mojtaba
Kiani
Golestan Research Center of Gastroenterology and Hepatology-GRCGH, Gorgan, Iran
mojtabakiani55@yahoo.com
N
Jamshid
Vafaeimanesh
Clinical Research Development Center, Qom University of Medical Sciences, Shahid Beheshti Hospital, Shahid Beheshti Boulevard, Qom, Iran
j.vafaeemanesh@muq.ac.ir
Y
Background: There have been reports on stent-related vascular erosions about patients with benign or malignant stenosis of the esophagus who received endoscopic stent insertion for palliative intention for oral intake.
Case presentation: A 61-year-old woman with esophageal cancer located in the middle part of esophagus was treated with esophagectomy. Two years following the surgery, malignant stenosis recurred in the esophagogastric anastomosis. A non-covered self-expanding metal stent (10 cm length with a diameter of 18 mm at expanded state) was inserted. Three months later, a massive hematemesis with subsequent hemorrhagic shock developed from the proximal end of the stent which resulted in the final diagnosis of arterioesophageal fistula on the left subclavian artery. An endovascular repair using a stent graft for the left subclavian artery via the right common iliac artery was performed and the patient remained well until discharge.
Conclusion: Increase in the treatment of esophageal strictures by stent insertion increases the risk of stent-related vascular fistula. These complications should be considered in any patients with massive upper gastrointestinal bleeding.
Subclavian artery-esophageal fistula, Metal stent, Esophagogastric anastomosis, Massive hematemesis
http://caspjim.com/article-1-468-en.html
http://caspjim.com/article-1-468-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Destructive effect of quinone-containing compounds on cytochrome P450: Arbutin as a double-edged sword
300
301
EN
Ahmad
Karkhah
Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Ahmadkarkhah@ymail.com
Y
Cyclosporin A, Oxidative stress, Arbutin, Cytochrome P450
http://caspjim.com/article-1-663-en.html
http://caspjim.com/article-1-663-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Prevalence of hepatitis A across various countries in the Middle East, African and Eastern European countries
302
303
EN
Abdolmajid
Ghasemian
Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
bacteriology94@gmail.com
Y
Hapatitis A, Iran, Middle East
http://caspjim.com/article-1-686-en.html
http://caspjim.com/article-1-686-en.pdf
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
2008-6172
7
4
2016
10
1
Erythema nodosum :what should we consider about it?
304
305
EN
Farhang
Babamahmoudi
Department of Infectious Diseases, University of Medical Sciences, Sari, Iran
stm.jmums@gmail.com
N
Arghavan
Amuzegar
Department of Infectious Diseases, University of Medical Sciences, Sari, Iran
stm.jmums@gmail.com
N
Tahoora
Mousavi
Molecular and Cell biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
stm.jmums@gmail.com
N
Lotfollah
Davoodi
Department of Infectious Diseases, University of Medical Sciences, Sari, Iran
lotfdavoodi@yahoo.com
Y
Erythema nodosum, Panniculitis, Erythematous
http://caspjim.com/article-1-702-en.html
http://caspjim.com/article-1-702-en.pdf