Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Correlation between Coronary Artery Calcification and COVID-19 in admitted patient
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0
EN
Saeed
Abrotan
Farzad
Jalali
Mohammad Taghi
Hedayati Goudarzi
Iraj
Jafaripour
mehrdad
saravi
naghmeh
ziaie amiri
Roghayeh
Pourkia
Kamyar
Amin
ali
bijani
Masoumeh
Bayani
soraya
khafri
Saeed
kargar-soleimanabad
erfan
ghadirzadeh
Abstract
Coronary heart disease (CHD) is an underlying cardiac condition contributing to increased COVID-19 mortality and morbidity which can be assessed by coronary artery calcification (CAC). The goal of this study was to find out if there were potential links between CAC, clinical findings, severity of COVID-19, and in-hospital outcomes. This retrospective study evaluated 551 suspected patients admitted to teaching hospitals of the Babol University of Medical Sciences, Babol, Iran, from March to October 2021. Data included previous diseases, comorbidities, clinical examinations, routine laboratory tests, demographic characteristics, duration of hospitalization, , and number of days under ventilation were recorded in a checklist. Our findings showed a significant relationship between CAC and in-hospital mortality of COVID-19 patients. CAC was also significantly related to age, duration of hospitalization, pulse rate, maximum blood pressure, ESR, BUN, neutrophil count, WBC count, and O2 saturation. However, it was not associated with the COVID-19 severity index, and logistic regression tests didn’t find a significant value of CAC to predict in-hospital mortality
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Focal epithelial hyperplasia (Heck's disease) in a Turkmen girl: a case report
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0
EN
Sudabeh
Baghery Moghadam
Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Fatemeh
Mirzaei
Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran
Shohreh
Ghasemi
Department of Oral and Maxillofacial surgery, The Dental College of Georgia at Augusta University, Augusta, Ga
Background: Focal epithelial hyperplasia (FEH) or Heck's disease is a condition of the oral mucosa defined by the asymptomatic presence of papules or nodules distributed in the oral mucosa, gingiva, tongue and lips. Heck's disease is most reported in the Native American and South African populations. It is mainly found in children with confirmed human papillomavirus (HPV) mostly HPV13 and 32. We report a rare case of Heck's disease in an Iranian-Turkmen girl with HPV6.
Case presentation: A 9-year-old Turkmen girl had esthetic and traumatic chief complaints caused by some enlarged lesions on her lips during the last six months. The patient did not have any systemic disease. Oral manifestations were white and pink nodules and papules on lips, buccal mucosa, and palate. Her mother had less than 10 similar lesions on her tongue and floor of the mouth that resolved, and only was papule was remained. HPV 6 was confirmed.
Conclusion: Patients with Heck's disease may be referred to an oral specialist, dermatologist, or otolaryngologist, so there should be enough knowledge about this condition among clinicians.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Hybrid Endoscopic and Laparoscopic En-bloc Resection for the Minimally Invasive Management of Gastrointestinal Stromal Tumors: A Case Report
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0
EN
Seyed Hassan
Abedi
Clinical Research Development Unit of Ayatollah Rouhani Hospital, Babol University of Medical Sciences & Health Services, Babol, Iran.
Pedram
Beigvand
Clinical Research Development Unit of Ayatollah Rouhani Hospital, Babol University of Medical Sciences & Health Services, Babol, Iran.
Reza
Mortazavi
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences & Health Services, Babol .Iran.
Sara
Babazade
Department of Pathology, School of Medicine, Babol University of Medical Sciences & Health Services, Babol, Iran.
Ali
Zahedian
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences & Health Services, Babol .Iran.
Background: Among mesenchymal tumors arising in the gastrointestinal tract, gastrointestinal stromal tumors are the most common. GISTs that do not have metastatic spread are treated surgically. Our case report aims to describe a newer & less invasive approach for resection of GISTs & early gastrointestinal tumors.
Case Presentation: An Iranian woman 41 years old with stomach stromal tumor is presented. Her complaint was minor epigastric discomfort. Tumor en-bloc resection was performed using a hybrid endoscopic-laparoscopic approach. She was doing very well & discharged the day after the operation.
Conclusion: GISTs and early gastrointestinal tumors can be treated with hybrid endoscopic and laparoscopic en-bloc resections instead of invasive surgery.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Case of cystic brain metastasis from lung adenocarcinoma
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0
EN
Danial
Fazilat-Panah
Cancer Research Center, Babol University of Medical Sciences, Babol, Iran
Ali
Shabestani Monfared
Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Hamid
Fallah Tafti
Radiotherapy Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Yazd, Iran
Nahid
Ahmadi
Cancer Research Center, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Siamak
Kazemi Soufi
Department of Orthopedics, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Western Azarbayejan, Iran
Ali
Emadi Torghabeh
Cancer Research Center, Mashhad University of Medical Sciences, Mashhad, Razavi Khorasan, Iran
Babak
PeyroShabany
Department of Internal Medicine, Sabzevar University of Medical Sciences, Sabzevar, Razavi Khorasan, Iran
Hassan
Younesi Ghale
Babol University of Medical Sciences, Babol, Mazandaran, Iran
Sara
Rasta
Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Alborz, Iran
Seyed Alireza
Javadinia
Non-Communicable Diseases Research Center, Sabzevar University of Medical Sciences, Sabzevar, Razavi Khorasan, Iran
Maedeh Alsadat
Fatemi
Cancer Research Center, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Ali
Alizadeh Khatir
Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Habibollah
Hasani
Clinical Research Development unit of Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Mazandaran, Iran
Background: Multiple cystic brain metastases are a rare form of cancer dissemination and usually originate from adenocarcinomas of the lung and breast. Managing these lesions is challenging, and cyst drainage plays an essential role in reducing intracranial pressure. This article presents a case of multiple cystic brain metastases from lung adenocarcinoma.
Case Presentation: A 40-year-old female with a two-year history of stage IV lung adenocarcinoma presented with debilitating progressive neurologic symptoms. Imaging studies showed multiple cystic lesions on brain MRI most consistent with brain metastases. She underwent a craniotomy to drain the biggest cysts, followed by whole-brain radiotherapy (WBRT). The patient experienced dramatic alleviation of symptoms. Following a year of follow-up, she had no neurological symptoms.
Conclusion: Despite the rarity of cystic brain metastases, these lesions should be ruled out in case of signs of increased intracranial pressure in a patient with a history of malignant disease.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
A case report of small cell carcinoma of uterine cervix
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0
EN
Danial
Fazilat-panah
Yavar
rajabzadeh
Mohammad hassan
emranpour
Babak
PeyroShabany
Sara
rasta
Maedeh alsadat
fatemi
delaram
ghadimi
zeinab
nazari
Background: Small cell carcinoma of cervix(SCCC) is a rare disease. SCCC is highly invasive and prone to distant metastatic spread and lymph node involvement. Here we aim to present a patient and her treatment
Case Presentation: we report 47-year-old patient with history of breast cancer manifesting with abnormal vaginal bleeding diagnosed with SCCC. Patient underwent radical hysterectomy and bilateral salpingo-oophorectomy. Then, she received adjuvant chemoradiation postoperatively.
Conclusion: Small cell carcinoma of cervix is an aggressive form of cervical cancer with poor prognosis. Optimal treatment remains unsettled.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
A cross-sectional study on non-infectious dysfunction of hemodialysis cuffed catheter
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0
EN
Pouya
Tayebi
Assistant Professor of Vascular Surgery, Department of Vascular and Endovascular Surgery, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Kosar
Hasanzadeh
Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
Masoumeh
Asgharpour
Assistant Professor of Nephrology, Department of Nephrology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Ali
Bijani
Social Determinant of Health Research Center, Babol University of Medical Sciences, Babol, Iran.
Naghmeh
Ziaie
Assistant Professor of Cardiology, Department of Cardiology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Background: Dialysis cuffed catheter dysfunction results in inadequate dialysis, increased sepsis risk, and a shortened catheter life. It may be possible to prolong catheter function by identifying the causes of cuffed catheter dysfunction.
Methods: This study was a cross-sectional descriptive study conducted in 2021-2022 on hemodialysis patients with jugular cuff catheters. The catheterizations were performed using the Seldinger technique and were confirmed by fluoroscopy. A 12-month follow-up was conducted with respect to the performance of the cuffed catheter.
Results: A total of 123 patients underwent hemodialysis over 2 years via a cuffed catheter. Catheters were most commonly inserted into the right internal jugular vein, with lengths of 19 cm (tip to cuff). The rate of dysfunction of cuffed catheters was 27.6%. Catheter-related thrombosis was the most common cause in 10 cases (29.4%), followed by catheter tip fibrin sheath in 8 cases (23.5%) and catheter tip malposition in 8 cases (23.5%). Furthermore, 18 patients (52.94%) of cuffed catheter dysfunction occurred within 3 months of catheter placement, based on our study. The dysfunction of cuffed catheters on the left side 23 (67.64%) is more prevalent than the right side 11 (32.35%) (p=0.043); the malposition of catheter tips is more prevalent on the left side (p=0.023).
Conclusion: Most commonly, cuffed catheter dysfunction is caused by thrombosis, fibrin sheath formation, and catheter tip malposition. Cuffed catheter failure can be reduced by carefully monitoring the catheter's path and tip position, searching for fibrin sheaths when investigating cuffed catheter failure, and preventing thrombotic events.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Diagnostic Options, Physiopathology, Risk Factors and Genetic Causes of Permanent Congenital Hypothyroidism; A Narrative Review
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0
EN
Zahra
Rasoulizadeh
Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Mahtab
Ordooei
Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Elahe
Akbarian
Children Growth Disorder Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Background: Permanent congenital hypothyroidism (PCH) is a lifelong condition characterized by a deficiency in thyroid hormone, leading to various neurodevelopmental complications. Early clinical signs are often nonspecific and easily overlooked, but newborn screening programs have improved early detection.
Methods: This narrative review aims to provide insights into into the comparison between transient and permanent PCH and also the diagnosis, risk factors, underlying pathophysiology, and genetic causes associated with PCH. Relevant studies were identified through a comprehensive search using the term 'Permanent congenital hypothyroidism' (Mesh) across scientific databases of electronic databases such as PubMed, Scopus, and Web of Science.
Results: Prompt initiation of thyroid hormone replacement therapy, particularly within the initial two weeks postpartum, crucially enhances neurocognitive development outcomes. Multiple predictive approaches, encompassing screening TSH levels, maternal thyroid history, and levothyroxine dosage per kilogram assessment, aid in identifying PCH. Recent studies demonstrate a mounting prevalence of PCH, contributing significantly to the overall rise in CH incidence. Genetic factors, primarily DUOX2 and DUOXA2 mutations, alongside environmental influences such as post-term birth, low birth weight, and macrosomia, may induce PCH. Nonetheless, reliable markers for early PCH prediction upon diagnosis remain elusive, leading to delayed recognition post-ceasing levothyroxine treatment around age 3.
Conclusions: Recent studies have observed an increased incidence of PCH, contributing substantially to the overall rise in cases of congenital hypothyroidism. Understanding the diagnostic options and genetic etiologies associated with PCH is crucial for early identification and appropriate management.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
Evaluation of the auditory brainstem response test in patients with the type 2 diabetes mellitus
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0
EN
Mahbubeh
Sheikhzadeh
Department of Audiology, School of Rehabilitation Sciences, Babol University of Medical Sciences, IR. Iran
Mohsen
Monadi
Department of Audiology, School of Rehabilitation Sciences, Babol University of Medical Sciences, IR. Iran
Mohammad Ali
Bayani
Clinical Research Development Unit of Rouhani Hospital, Department of Internal Medicine, Babol University of Medical Sciences, Babol, Iran.
Fereshteh
Bagheri
Department of Audiology, School of Rehabilitation Sciences, Babol University of Medical Sciences, IR. Iran
Milad
kami
Department of Medicine, Babol University of Medical Sciences, IR. Iran
Background: The aim of this study was to evaluate hearing function using auditory brainstem response (ABR) in patients with diabetes.
Method: The present case-control study was performed on thirty diabetes patients as a case group and thirty healthy individuals as a control group. Baseline demographic information, HbA1c level, and duration of diabetes were obtained from all diabetes patients. In all subjects, the ABR and pure-tone audiometry (PTA) tests were performed and the results were analyzed using the t-test and logistic regression.
Results: The absolute latency of I was significantly lower in diabetes patients. The absolute latency of III and the interpeak latencies (IPL) I-III were significantly higher in diabetic patients. No significant relationship was noticed in the absolute latency of V and the IPL I-V among diabetes patients in the right and left ears.
Conclusion: The results of this study suggested that the diabetes may cause central auditory dysfunction manifested on the absolute latency of III, the IPL I-III and III-V.
Babol University of Medical Sciences
Caspian Journal of Internal Medicine
2008-6164
In Press
1
An investigation of the Effect of Antihypertensive drugs on Arteriovenous Fistula Maturation in Patients with Hemodialysis
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0
EN
Fatemeh
Mahmoudlou
Medical Doctor, Student Research Committee, Babol University of Medical Sciences, Babol, Iran
Pouya
Tayebi
Assistant Professor of Vascular Surgery, Department of Vascular and Endovascular Surgery, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
Aliakbar
Moghadamnia
Professor of Pharmacology, Department of Pharmacology and Toxicology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
Ali
Bijani
Associate Professor of Epidemiology, Social Determinants of Health Research Center, Babol University of Medical Sciences, Babol, Iran
Background: The maturation of the Arteriovenous Fistula (AVF) is necessary for successful hemodialysis treatment. However, the role of antihypertensive drugs in influencing AVF maturation remains uncertain. This study investigated the AVF maturation in patients with renal failure treated with antihypertensive medications.
Methods: A prospective cohort study was conducted on 73 patients who needed to be treated with hemodialysis through AVF. Demographic information, medication, underlying diseases, blood pressure changes, surgical information, and the time of AVF maturation were collected during the study. Descriptive statistics and survival analysis were employed to assess the outcomes.
Results: The mean age of patients was 53.96 ± 13.65 years, with 38 (52.1%) males and 35 (47.9%) females. The mean AVF maturation time was 104.87 ± 1.02 days, and the rate of AVF maturation was 87.7%. Among the comorbidities, the rate of AVF maturation in diabetic patients (78.4%) versus non-diabetic (97.2%) exhibited a notably diminished effect (P = 0.028). There was a significant association between mean intraoperative arterial blood pressure (123.45 ± 2.89 mmHg) and AVF maturation time (P = 0.033). Furthermore, there weren’t any significant differences in the use of antihypertensive medications on AVF maturation time or rates.
Conclusion: Our study findings suggest that the administration of antihypertensive medications did not demonstrate a significant correlation with either the AVF maturation outcome or the time required for maturation.