:: Volume 8, Issue 3 (6-2017) ::
Caspian J Intern Med 2017, 8(3): 153-158 Back to browse issues page
Casual role of infectious agents in cancer: An overview
Jila Masrour-Roudsari, Soheil Ebrahimpour *
Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. , drsoheil1503@yahoo.com
Abstract:   (5695 Views)

Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue. Moreover, among these factors, infection and its association to cancers is controversial. Although, it seems that the genome instability of the cells can initiate cancer development. The purpose of this review was to present the role of infection in the development of cancer. Infectious agents, such as hepatitis B (HBV) and C viruses (HCV), Epstein-Barr virus (EBV), human papillomavirus (HPV), human immunodeficiency virus type 1 (HIV-1), Helicobacter pylori (H. pylori) and Streptococcus bovis (S. bovis)  contribute to the pathogenesis of different cancers. These cancers include hepatocellular carcinoma, Burkitt's lymphoma, nasopharyngeal carcinoma, cervical cancers, non-Hodgkin lymphoma, Kaposi sarcoma, adenocarcinoma and lymphoma. Screenings of infectious diseases in cancer patients may open up areas of research in the identification of optimizing cancer control strategies. 

Keywords: Infection, Cancer, Prevention, Virus, Bacteria
Full-Text [PDF 429 kb]   (1124 Downloads)    
Type of Study: Review Article | Subject: Infectious Diseases
Received: 2017/05/14 | Accepted: 2017/06/12 | Published: 2017/06/12

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Volume 8, Issue 3 (6-2017) Back to browse issues page