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:: دوره 2، شماره 3 - ( 10-1389 ) ::
جلد 2 شماره 3 صفحات 256-260 برگشت به فهرست نسخه ها
Seroprevalence of anti-Hp and anti-CagA antibodies among healthy persons in Golestan province, northeast of Iran (2010)
چکیده:   (7765 مشاهده)
Background: The major cause of peptic ulcer disease is helicobacter pylori (Hp), and it is also implicated in the pathogenesis of adenocarcinoma of the distal stomach and gastric lymphoma. The incidence of peptic ulcer disease, atrophic gastritis, and gastric adenocarcinoma are more common in people infected of cagA positive strains of Hp. The aim of this study was to determine the prevalence of the anti-Hp and anti-cagA antibodies among healthy persons in Golestan province-North of Iran.
Methods: The blood samples of 1028 healthy people were collected all over Golestan province by cluster sampling. A demographic questionnaire was completed and body mass index (BMI) was calculated for each case. Hp-IgG (Pishtaz teb Co. Iran) and anti- cagA (DIA.PRO Italy) titer were evaluated by Elisa method. Data were collected and analyzed.
Results: Six hundred-eighty three individuals (66.4%) were positive for Hp and 395 (57.8%) of them were cagA positive. Hp positive cases were (66.3%) and (66.6%) in male and female, respectively. Prevalence of cagA was 56.3% and 58.9%, respectively. The most seropositivity of Helicobacter Pylori (75.4%) was in 55-64 years old (p<0.001). Prevalence of cagA (63.4%) was more in age between 15-24 years.
Conclusion: Prevalence of anti-Hp antibody and strains of cagA seropositive in healthy persons of this province of Iran were relatively high. Preventive protocol for reducing of the infection is recommended.
متن کامل [PDF 150 kb]   (1911 دریافت)    
نوع مطالعه: Original Article | موضوع مقاله: Infectious Diseases
دریافت: 1392/10/25 | پذیرش: 1392/10/25 | انتشار: 1392/10/25
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Ghasemi Kebria F, Bagheri H, Semnani S, Ghaemi E. Seroprevalence of anti-Hp and anti-CagA antibodies among healthy persons in Golestan province, northeast of Iran (2010). Caspian J Intern Med. 2011; 2 (3) :256-260
URL: http://caspjim.com/article-1-116-fa.html

Seroprevalence of anti-Hp and anti-CagA antibodies among healthy persons in Golestan province, northeast of Iran (2010). 1. 1389; 2 (3) :256-260

URL: http://caspjim.com/article-1-116-fa.html



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دوره 2، شماره 3 - ( 10-1389 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
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