[صفحه اصلی ]   [Archive]  
:: صفحه اصلي :: درباره نشريه :: آخرين شماره :: تمام شماره‌ها :: جستجو :: ثبت نام :: ارسال مقاله :: تماس با ما ::
:: دوره 12، شماره 2 - ( 12-1399 ) ::
جلد 12 شماره 2 صفحات 124-128 برگشت به فهرست نسخه ها
The Role of microRNA in Cancer Cachexia and Muscle Wasting: A Review Article
چکیده:   (312 مشاهده)
Almost half of cancer patients experience cachexia syndrome. Cachexic patients are at risk of increased side effects of chemotherapy, reduced tolerance to chemotherapy drugs, longer duration of treatment period, and decreased quality of life. Cancer cachexia is a multifactorial syndrome. Micro ribonucleic acid (miRNA), a “non-coding RNA”, is considered to be a risk factor of cachexia and muscle wasting in cancer patients. miRNA has a role in affecting protein regulation, associated with different inflammatory and disease pathways. miRNA can also affect cytokines or directly change the regulation of metabolism that lead to cachexia. In this review, we want to focus on the pathophysiology to give a better understanding about the role of miRNA in the development of cancer cachexia. Based on various pathways of miRNA in cancer cachexia, it can be a potential target for therapeutic strategies. Improved knowledge about miRNA can give the opportunity to develop new treatment in the management of cancer cachexia.
متن کامل [PDF 184 kb]   (141 دریافت)    
نوع مطالعه: Review Article | موضوع مقاله: Oncology
دریافت: 1398/10/30 | پذیرش: 1399/5/6 | انتشار: 1399/12/30
ارسال نظر درباره این مقاله
نام کاربری یا پست الکترونیک شما:

CAPTCHA



XML   English Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Sutandyo N. The Role of microRNA in Cancer Cachexia and Muscle Wasting: A Review Article. Caspian J Intern Med. 2021; 12 (2) :124-128
URL: http://caspjim.com/article-1-2181-fa.html

The Role of microRNA in Cancer Cachexia and Muscle Wasting: A Review Article. 1. 1399; 12 (2) :124-128

URL: http://caspjim.com/article-1-2181-fa.html



دوره 12، شماره 2 - ( 12-1399 ) برگشت به فهرست نسخه ها
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.04 seconds with 30 queries by YEKTAWEB 4299