[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 13 - Covid 19 Supplement 2 ::
Caspian J Intern Med 2022, 13 - Covid 19 Supplement 2: 148-154 Back to browse issues page
Impact of Hypertension and Physical Fitness on SARS-COV-2 and related Consequences. (Possible mechanisms with focusing on ACE2)
Mehdi Kushkestani * , Mohsen Parvani , Mahsa Moghadassi , Yaser Kazemzadeh , Kiandokht Moradi
Faculty of Physical Education and Sport Sciences, Allameh Tabataba'i University, Tehran, Iran , mehdi.kushk@gmail.com
Abstract:   (1494 Views)
Hypertension disease as an absolute risk factor of Covid-19 disease has been well-proven in recent evidence. The factors such as the use of antihypertensive drugs, protein expression, and compensatory axes resulted in hypertension disease playing very important roles in the occurrence of this problem. In this review study, we first attempted to investigate the higher chance reason for Covid-19 disease in people with high blood pressure; then we examined the related mechanisms, and finally, we reported the differences and similarities between people with high blood pressure and athletes. All in all, we concluded that people who exercise regularly, the same as hypertensive patients (Compensatory mechanism) are more susceptible to COVID-19 infection due to the high concentration of ACE2 (Physiological mechanism) caused by exercise adaptation, but for the low level of ANG2 (Systematic and gene expression) these individuals (Active subjects) indicate fewer complications and severity symptoms of COVID-19  such as dyspnea, hospitalization and, heart disease compared with hypertensive patients.
Keywords: SARS-CoV-2, Hypertension, Exercise, Angiotensin-converting enzyme 2, Physical Fitness, Renin-Angiotensin System
Full-Text [PDF 257 kb]   (411 Downloads)    
Type of Study: Review Article | Subject: Imonology
Received: 2020/10/15 | Accepted: 2021/02/20 | Published: 2022/04/6
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Kushkestani M, Parvani M, Moghadassi M, Kazemzadeh Y, Moradi K. Impact of Hypertension and Physical Fitness on SARS-COV-2 and related Consequences. (Possible mechanisms with focusing on ACE2). Caspian J Intern Med 2022; 13 :148-154
URL: http://caspjim.com/article-1-2550-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 13 - Covid 19 Supplement 2 Back to browse issues page
Caspian Journal of Internal Medicine
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4570