Background: HELLP syndrome is an important
complications in pregnancy which increases maternal and fetal mortality. This disease
usually remits with supportive treatment which includes prescription of
corticosteroid, magnesium sulfate, stabilization of mother and pregnancy
termination. Plasmapheresis is a treatment of choice which improves clinical
outcomes in complicated cases.
Case presentation: A 22-year-old woman with coagulopathy and
respiratory distress and 33-year-old woman with a history of cerebellar
medulloblastoma at 32-weeks’ gestation developed thrombocytopenia due to HELLP
syndrome were treated with plasmapheresis were described.
Conclusion: Plasmapheresis can significantly improve the outcome
of patients with HELLP syndrome who are unresponsive to conservative therapy
