Low baseline serum albumin a predictor of anemia in patients on chronic hemodialysis
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Behzad Heidari , Hasan Taheri , Karimollah Hajian-Tilaki , Mehdi Yolmeh , Roghayeh Akbari |
Babol University of Medical SciencesBabol , Rghayeh.akbari@yahoo.com |
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Abstract: (10752 Views) |
Background: Inflammatory process has a substantial contribution in
the development of anemia in chronic hemodialysis patients. Low serum albumin
in hemodialysis patients is considered a marker of inflammation. The present
longitudinal study aimed to determine the relationship between low baseline
serum albumin and future development of anemia. Methods: The population of this study consisted of all
patients on standard maintenance hemodialysis for at least three months or
longer. Patients were classified as high or low serum albumin level (≥ or <
3.9 gr/dl). All patients received the standard treatment of anemia. The main
objective of this study was to compare the prevalence of anemia defined as
hemoglobin levels < 11 gr/dl between the two study groups at the end of the
study period. Results: A total of 82 patients (50% females) with
mean±SD age of 55±16.8 years and mean dialysis duration of 5.2±4
years were followed-up for an average
period of 10±1 (range, 8-11) months,
however 48 patients with high serum albumin and 24 patients with low serum albumin group completed the study. At
baseline, the two groups were similar regarding hemoglobin (9.8±1.2 vs 9.16±1.6
gr/dl, P=0.95) levels. At endpoint, prevalence of
anemia in high albumin group was significantly lower than the low albumin group
(50% versus 83.3% P=0.005). Conclusion: The findings of this study indicate that low serum
albumin in hemodialysis patients is a predictor of anemia indicating
unresponsiveness to conventional treatment of anemia. |
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Keywords: Hemodialysis, Anemia, Serum Albumin |
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Full-Text [PDF 231 kb]
(2986 Downloads)
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Type of Study: Original Article |
Subject:
Nephrology Received: 2015/06/10 | Accepted: 2015/06/22 | Published: 2015/06/22
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