:: Volume 7, Issue 3 (7-2016) ::
Caspian J Intern Med 2016, 7(3): 153-161 Back to browse issues page
Determinants of pain in patients with symptomatic knee osteoarthritis
Behzad Heidari, Karimollah Hajian-Tilaki, Mansour Babaei *
Department of Internal medicine, Ayatollah Rouhani Hospital Division of Rheumatology, Babol University of Medical Sciences, Babol, Iran , babaeim47@yahoo.com
Abstract:   (9276 Views)

Background: Several factors are associated with the development or exacerbation of pain in knee osteoarthritis (KOA). In this study, we reviewed this context based on relevant studies.

Methods: Recent published studies which have addressed the relationship between pain and KOA were summarized.

Results: Correlates of the clinical, demographic features, laboratory tests and abnormalities on radiographic as well as magnetic resonance imaging (MRI) with the knee pain have been discussed. The results indicated that many factors such as synovitis, synovial effusion, obesity, as well as structural lesions determined by MRI or radiographic examination, serum cytokines, inflammatory markers are determinants of pain in KOA.

Conclusion: This context requires further investigations for identification of additional factors which initiate pain in asymptomatic KOA

Keywords: Knee osteoarthritis, Pain, Determinants, Synovitis, C-reactive protein, Structural lesions
Full-Text [PDF 297 kb]   (1959 Downloads)    
Type of Study: Review Article | Subject: Reumatology
Received: 2016/04/11 | Accepted: 2016/06/6 | Published: 2016/06/6


XML     Print



Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 7, Issue 3 (7-2016) Back to browse issues page