%0 Journal Article %A Abbaszade Marzbali, Nargeuss %A Zabihi, Ebrahim %A Magne, Nicolas %A Vallard, Alexis %A Moslemi, Mohammad %A Moslemi, Dariush %T Recover burn ointment for managing acute radiodermatitis in patients with breast cancer: A double blind randomized controlled trial %J Caspian Journal of Internal Medicine %V 13 %N 2 %U http://caspjim.com/article-1-2568-en.html %R 10.22088/cjim.13.2.5 %D 2022 %K breast cancer, radiotherapy, radiodermatitis, Recove ointment, radiation therapy oncology group., %X Background: Radiodermatitis is the most common complication of radiotherapy. There is no gold standard for managing the radiodermatitis. This study aimed to evaluate the effect of topical Recove® burn ointment; basically compounded of sesame oil, camphor, and zinc oxide; in preventing acute radiodermatitis. Methods: This double blind RCT (IRCT No.: 201204047136N2) was performed on 71 patients that referred for radiotherapy after mastectomy to Shahid Rajaee Hospital (Babolsar-Iran) during 2013-2017. Patients were allocated into 2 groups; 34 in control group and 37 in Recove® group. Patients applied the ointment 2 times a day, before every radiation therapy session for 5 weeks. The radiation oncologist assessed the severity of dermatitis weekly for 5 weeks and graded it from 0 to 4 according to the RTOG criteria. Results:Baseline characteristics including age, and BMI had no significant difference between groups. The Recover group patients experienced significantly less severe dermatitis compared to the controls (p<0.001). None of the patients in Recove® group encountered more than grade 2 of RTOG criteria, however, in the control group, 4 (12.9%)patients experienced grade 3 of RTOG and 3 (9.7%)patients developed grade 4 of RTOG at the end of the 5th week. Conclusion: Our results indicate that Recove® ointment significantly reduces the severity of acute radiodermatitis. %> http://caspjim.com/article-1-2568-en.pdf %P 349-355 %& 349 %! Application of RecoveĀ® in radiodermatitis %9 Original Article %L A-10-2034-1 %+ Babol University of Medical Sciences %G eng %@ 2008-6164 %[ 2022