TY - JOUR JF - babol-caspjim JO - Caspian J Intern Med VL - 3 IS - 1 PY - 2012 Y1 - 2012/1/01 TI - How is total antioxidant status in plasma of Patients with brucellosis? TT - N2 - Background: Brucella species can cause infection in a wide range of animals and human beings. Oxidative events against brucella infection are not well elucidated. It is possible that brucellosis may be related to increased free radical production and antioxidant depletion. Thus, the aim of this study was to determine the total antioxidant capacity (TAC) before and after treatment of patients with brucellosis. Methods: In the present study, a total of 48 patients with brucellosis, 23 males and 25 females, were detected through Wright 𕟳/160 2ME 𕟳/80, in association with compatible clinical findings. All patients were treated with standard regimens of therapy. Total antioxidant capacity (TAC) was determined with ferric reducing antioxidant power (FRAP) using spectrophotometric method before and after treatment. Results: TAC levels were significantly lower in pre-treatment than in post-treatment patients, 0.783±0.015 and 0.819±0.024 m mol/L respectively (p SP - 363 EP - 367 AU - Gholami, Mehdi AU - Hasanjani Roushan, Mohammadreza AU - Mahjoub, Soleiman AU - Bijani, Ali AD - KW - Acute brucellosis KW - Free radical KW - Oxidative stress KW - Total antioxidant UR - http://caspjim.com/article-1-133-en.html ER -