en Cardiology Cardiology Original Article Original Article <span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background:</em></strong> </span>Coronary artery disease (CAD) is one of the most progressive and life-threatening diseases and is the first leading cause of death affecting both genders in Iran. The present study aimed to determine the extent of coronary vessel involvement and relevant relationship with several underlying risk factors.<br> <span style="color:#0000FF;"><strong><em>Methods:</em></strong> </span>In this cross-sectional study, 1452 patients undergoing angiography who met the inclusion criteria were recruited consecutively in Babol, Iran during 2016. Data collection was performed through a questionnaire including demographic and clinical characteristics and information on underlying diseases via an interview with the patient and looking into the patients&rsquo; records.<br> <span style="color:#0000FF;"><strong><em>Results:</em></strong></span> Of these patients, 459 (31.6%) had normal coronary arteries, 220 (15.1%) suffered from non-obstructive CAD and 773 (53.3%) had one, two or three-vessel obstructive involvement. The results of multiple logistic regression showed that the chances of having coronary artery involvement in patients with diabetes (OR=1.55, p=0.012), age> 60 years old (OR=3.52, P=0.001), male gender (OR=2.54, P=0.001), history of heart attack (OR=3.16, P=0.001), and history of hospitalization because of cardiac problem (OR=1.51, P=0.021) significantly increased.<br> <span style="color:#0000FF;"><strong><em>Conclusions:</em></strong></span> Diabetes, male gender, age over 60 years old, history of myocardial infarction and history of hospitalization due to cardiac problem were related to the extent of coronary vessels involvement. Therefore, it is recommended to practice preventive measures more extensively in this regard.</span><br> &nbsp; Risk factors, Coronary Angiography, Coronary Vessels, Coronary Stenosis 361 367 http://caspjim.com/browse.php?a_code=A-10-1006-1&slc_lang=en&sid=1 Fahimeh Kazemian khafri@yahoo.com 100319475328460014045 100319475328460014045 No Non-Communicable Pediatric Diseases Research Centers Health Research Insitute, Babol University of Medical Sciences, Babol, Iran seyed farzad jalali Sfjalali42@yahoo.com 100319475328460014046 100319475328460014046 No Department of Cardiology, Clinical Research Development unit of Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran Karimolah Hajian-Tilaki drhajian@yahoo.com 100319475328460014047 100319475328460014047 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Afsaneh Arzani ARZANIAF@GMAIL.COM 100319475328460014048 100319475328460014048 Yes Nursing Care Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Kamyar Amin persicakamyar@yahoo.com 100319475328460014049 100319475328460014049 No Department of Cardiology, Clinical Research Development unit of Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran