Caspian Journal of Internal Medicine

en Libman-Sacks endocarditis in patients with systemic lupus erythematosus with secondary antiphospholipid syndrome Reumatology Reumatology case report case report Background: Libman-Sacks endocarditis (LSE) is characterized by sterile lesions that commonly affect the aortic and mitral heart valves. Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) have been associated with LSE. Cardiac manifestations including LSE could be interrelated with other manifestations and early diagnosis could help in preventing further complications. Case presentation: Here, we report three cases of LSE in SLE patients with secondary APS. All patients presented with neurological manifestations and LSE was diagnosed by Transesophageal echocardiography (TEE). All three patients were treated for the underlying disease and also received anticoagulant therapy. Conclusion: In all patients with SLE and secondary APS, LSE should be considered if a patient manifests any evidence of neurologic involvement. Systemic lupus erythematosus, Antiphospholipid syndrome, Libman-Sacks endocarditis 339 342 http://caspjim.com/browse.php?a_code=A-10-1142-2&slc_lang=en&sid=1 Yousef Mohammadi Kebar kebarym@gmail.com 100319475328460018109 100319475328460018109 No Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Leili Avesta avestaleili@yahoo.com 100319475328460018110 100319475328460018110 No Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Afshin Habibzadeh afshin.habibzadeh@gmail.com 100319475328460018111 100319475328460018111 Yes Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran Mehdi Hemmati Mehdi.hemmati@medstar.net 100319475328460018112 100319475328460018112 No Department of Medicine, Medstar Health (Baltimor)/ Medstar Georgetown University Hospital, Washington, D.C., USA