en Neurology Neurology Original Article Original Article <span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em></span> With the growing population of the elderly, the prevalence of disabilities and chronic diseases will also likely increase. Muscle weakness leads to low amounts of physical activity in elderly diabetic patients and makes them susceptible to falls. In this study, we aimed to compare the muscle strength between diabetic and non-diabetic elderly individuals.<br> <span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em></span> The present study is part of the the Amirkola Health and Ageing Project (AHAP) cohort performed on 1320 elderly individuals. Diabetic and non-diabetic subjects were considered as case and control groups, respectively. A diagnosis of diabetes was assigned to patients who were previously diagnosed and those with repeated fasting blood sugar FBS&ge;126mg/dl. Digi Hand Dynamometer device and manual muscle testing (MMT) grading systems were used to assess muscle force in the upper and lower extremities, respectively. Data were then analyzed and p<0.05 was considered significant.<br> <span style="color:#0000FF;"><strong><em>Results</em></strong><em>:</em></span> 29.8% of the total participants (n=393) were diabetics. In the case group, 143 (36.4% of all diabetics) had weak upper extremity muscles. The number was 314 (33.9%) among non-diabetics (P=0.38). We saw decreased lower extremity muscle force in 134 (34.1%) diabetic individuals and 292 (31.5%) non-diabetics (P=0.35). Statistical analysis showed no significant difference in any of the lower or upper extremity muscle forces between diabetics and non-diabetics (p>0.05).<br> <span style="color:#0000FF;"><strong><em>Conclusion</em></strong><em>:</em></span> Our findings indicate that diabetes mellitus (DM) affects neither the upper nor the lower extremity muscle force in the elderly.</span> Elderly, Diabetes, Muscle force 265 270 http://caspjim.com/browse.php?a_code=A-10-176-3&slc_lang=en&sid=1 Mohammad Rahimi rohanresearch88@gmail.com 100319475328460018042 100319475328460018042 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Payam Saadat sepanta1968@yahoo.com 100319475328460018043 100319475328460018043 Yes Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Seyed reza Hosseini seidrezahosseini@yahoo.com 100319475328460018044 100319475328460018044 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Mohammadali Bayani bayanima49@yahoo.com 100319475328460018045 100319475328460018045 No Clinical Research Development Unit of Ayatollah Rouhani Hospital, Department of Internal Medicine, Babol University of Medical Sciences, Babol, Iran Ali Bijani drbijani@yahoo.com 100319475328460018046 100319475328460018046 No Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran