en Neurology Neurology Case Series Case Series <span style="font-size:14px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em></span> Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system which damages the myelin and axon. Primary biliary cholangitis (PBC) is a slow progressive liver disease with autoimmune feature in which non-purulent destructive cholangitis and interlobular bile duct destruction occur. Involvement of each of PBC and MS is thought to be related to environmental exposure in genetically susceptible persons.<br> <span style="color:#0000FF;"><strong><em>Case Presentation:</em></strong></span> Here, we aim to report 3 women 52, 27 and 51 years old with MS and PBC.<br> <span style="color:#0000FF;"><strong><em>Conclusion:</em></strong> </span>Although MS seems to have an association with some autoimmune gastrointestinal disorders such as ulcerative colitis, the concurrence of MS and PBC has been rarely reported</span></span> Multiple sclerosis, primary biliary cholangitis, autoimmune disorders 223 226 http://caspjim.com/browse.php?a_code=A-10-1270-2&slc_lang=en&sid=1 Mokhgan Sattar mozhgan_sattar@yahoo.com 100319475328460021802 100319475328460021802 No Clinical Neurology Research Center, Shiraz university of Medical Sciences, Shiraz, Iran Maryam Poursadeghfard poursadra@gmail.com 100319475328460021803 100319475328460021803 Yes Clinical Neurology Research Center, Shiraz university of Medical Sciences, Shraz, Iran.