en Orthopedy Original Article Original Article <span style="font-size:12px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em></span> Distal radius fractures constitute 17% of all fractures and 75% of forearm fractures in adults. Due to the vital role of the hands in a wide range of daily tasks, quick recovery and fewer complications for the patients are important. The purpose of this study was to compare the two common treatments of distal radius fractures namely, percutaneous pinning and pin-in-plaster.<br> <span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em> </span>An observational analytical cohort study was conducted on 74 patients with distal radius fracture treated with percutaneous pinning fixation and pin-in-plaster techniques. The patients, aged more than or equal to 18 years with unilateral, closed and unstable distal radius fractures were treated in Shahid Beheshti Hospital during 2007 to 2010.The data were entered into the SPSS Version 20 statistical software and analyzed by student&rsquo;s t-test, one-way ANOVA and repeated measures test.<br> <span style="color:#0000FF;"><strong><em>Results</em></strong><em>:</em> </span>Randomly, 31 patients were in pin-in-plaster group and 43 patients in percutaneous pinning group. The patients&rsquo; age range was 18-74 years. The average of radial inclination and palmar tilt after 6 weeks was significant (P=0.02, p<0.0001) in patients with percutaneous pinning. The performance of the patients after 3 and 12 months in both groups was significant (p=<0.0001).<br> <span style="color:#0000FF;"><strong><em>Conclusion</em></strong><em>:</em> </span>This study revealed that in approach to unstable DRF in adults, PCP method shows better improvement compared to PP technique.</span></span> Keywords: Distal radius fracture, Percutaneous pinning, Pin in plaster, Fracture 309 313 http://caspjim.com/browse.php?a_code=A-10-1305-1&slc_lang=en&sid=1 Farhang Tajeddin bcrdc90@yahoo.com 100319475328460018082 100319475328460018082 No Student Research Committee, Babol University of Medical Science, Babol, Iran Seyyed Mokhtar Esmaeilnejadganji smsnganji@yahoo.com 100319475328460018083 100319475328460018083 No Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Behnam Baghiani Moghaddam behnam.baghiani@gmail.com 100319475328460018084 100319475328460018084 No Department of Orthopedic surgery, School of Medicine, Babol University of Medical Sciences, Babol, Iran Sekineh Kamali Ahangar otaghsara2@gmail.com 100319475328460018085 100319475328460018085 No Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol,Iran Masood Bahrami feridoni Dr bahrami865@gmail.com 100319475328460018086 100319475328460018086 Yes Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran