en Hematology Hematology Original Article Original Article <span style="font-size:12px;"><span style="font-family:times new roman;"><span style="color:#0000FF;"><strong><em>Background</em></strong><em>:</em> </span>Neutrophil-lymphocyte ratio (NLR), lymphocyte-monocyte ratio (LMR) and platelet-lymphocyte ratio (PLR) have a prognostic value in several types of diseases such as cancers and they vary in different races. So, we aimed to evaluate the normal range of these markers among healthy people to determine the normal value in Iranian population.<br> <span style="color:#0000FF;"><strong><em>Methods</em></strong><em>:</em></span> In the present study, cross-sectional data of population-based cohort study named &ldquo;Tabari cohort study&rdquo; was utilized. In the first phase of Tabari cohort, 10255 participants aged 35-70 years from urban and rural areas of Sari, Mazandaran, Iran entered into the study. The study included a questionnaire survey and blood collection. Blood samples were collected after 12 hours fasting from all participants during the study. Hematological indices were measured for all samples using Celltac Alpha&nbsp;MEK-6510 K (Tokyo, Japan).<br> <span style="color:#0000FF;"><strong><em>Results</em></strong><em>:</em> </span>After sample exclusion, 2212 healthy subjects of Tabari&#39;s normal cohort population were investigated. The mean age of the samples was 47.9&plusmn;9.29 years. The mean of NLR, LMR, PLR were 1.70&plusmn;0.70, 11.15&plusmn;3.14 and 117.05&plusmn;47.73, respectively.<br> <span style="color:#0000FF;"><strong><em>Conclusion</em></strong><em>:</em></span> Our investigation provides preliminary reference values for NLR, LMR, and PMR among Iranian population that can be used for disease progress in various clinical procedures.</span></span> Normal values, neutrophils-lymphocytes ratio, lymphocytes-monocytes ratio, platelets-lymphocytes ratio 320 325 http://caspjim.com/browse.php?a_code=A-10-672-1&slc_lang=en&sid=1 Mahmood Moosazadeh mmoosazadeh1351@gmail.com 100319475328460018091 100319475328460018091 No Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran Iradj Maleki iradj2001@yahoo.com 100319475328460018092 100319475328460018092 No Gut and Liver Research Center, Mazandaran university of medical sciences, Sari, Iran Reza Alizadeh-Navaei reza_nava@yahoo.com 100319475328460018093 100319475328460018093 Yes Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran Motahareh Kheradmand elham.kherad@gmail.com 100319475328460018094 100319475328460018094 No Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran Akbar Hedayatizadeh-Omran akbar_hedayati@yahoo.com 100319475328460018095 100319475328460018095 No Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran Amir Shamshirian shamshirian.amir@gmail.com 100319475328460018096 100319475328460018096 No Department of Medical Laboratory Sciences, Student Research Committee, School of Allied Medical Sciences, Mazandaran University of Medical Sciences, Sari, Iran Agil Barzegar dr.aghil_barzegar@yahoo.com 100319475328460018097 100319475328460018097 No Gastrointestinal Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran