en psychiatry psychiatry Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><strong><em>Background</em></strong><em>:</em></span> This study was conducted to determine the prevalence of metabolic syndrome (Mets) in schizophrenic patients in a 6-month period of treatment with antipsychotic medications.<br> <span style="color:#0000ff;"><strong><em>Methods</em></strong><em>:</em></span> In this study, 60 volunteer schizophrenic patients were included. At the onset and 6 months after treatment with antipsychotic medications, fasting blood sugar (FBS), serum triglyceride (TG), high density lipoprotein (HDL), weight, waist circumference (WC), and blood pressure were determined. We defined Mets according to ATPIII criteria.<br> <span style="color:#0000ff;"><strong><em>Results</em></strong><em>:</em></span> After a 6-month treatment with antipsychotic drugs, the mean WC, serum TG, HDL, systolic and diastolic blood pressure increased but the changes of WC and HDL were statistically significant (p<0.05). We found that the percentage of patients with high WC, low HDL levels, and Mets increased after treatment which was statistically significant (p<0.05).<br> <span style="color:#0000ff;"><strong><em>Conclusion</em></strong><em>:</em></span> It is recommended that nutritional and lifestyle changes intervention should be implanted for schizophrenic patients undergoing treatment.</span></span> schizophrenic patients, metabolic syndrome, metabolic syndrome components 310 314 http://caspjim.com/browse.php?a_code=A-10-1556-1&slc_lang=en&sid=1 Elnaz Faramarzi elnazfaramarzi849@gmail.com 100319475328460023633 100319475328460023633 Yes Liver and Gastrointestinal Diseases Research center, Tabriz University of Medical sciences,Tabriz, Iran Nayyer Jaberi Nayyer.jaberi@gmail.com 100319475328460023634 100319475328460023634 No Research center of psychiatry and behavioral sciences, Tabriz University of Medical sciences, Tabriz, Iran Mostafa Farahbakhsh mfarahbakhsh@gmail.com 100319475328460023635 100319475328460023635 No Research center of psychiatry and behavioral sciences, Tabriz University of Medical sciences, Tabriz, Iran alireza Ostadrahimi ostadrahimi@tbzmed.ac.ir 100319475328460023636 100319475328460023636 No Nutrition Research center, Tabriz University of Medical sciences, Tabriz, Iran Mohammad Asghari Jafarabadi m.asghari862@gmail.com 100319475328460023637 100319475328460023637 No Medical Education Research Center, Department of Statistics and Epidemiology, Faculty of Health, Tabriz University of Medical Sciences, Tabriz, Iran Ali Fakhari a_fakhari@yahoo.com 100319475328460023638 100319475328460023638 No Research center of psychiatry and behavioral sciences, Tabriz University of Medical sciences, Tabriz, Iran