Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1399
10
1
gregorian
2021
1
1
12
1
online
1
fulltext
en
Relationship between clinical and laboratory findings of rheumatoid arthritis patients with their oral status and disease activity
Reumatology
Reumatology
Original Article
Original Article
<span style="font-size:14px;"><span style="font-family:Times New Roman;"><strong><em><span style="color:#0000ff;">Background:</span> </em></strong>Rheumatoid arthritis (RA) is the most common chronic inflammatory joint disease. Complications of RA can cause low quality of life and disabilities. Nowadays, despite all the medical developments, etiology of RA is unclear. Both soft and hard tissue damages occur in RA and periodontitis due to chronic inflammation and also since tissue damage presentation and pathogenesis of RA and periodontitis are the same, this study was done for evaluating the relationship between clinical and laboratory findings in RA patients with their oral status and disease activity.<br>
<span style="color:#0000ff;"><strong><em>Methods:</em></strong></span> This case-control study was performed on 236 patients; 118 RA patients and 118 cases of normal people. Gingivitis, dental caries and plaques, oral hygiene and severity of periodontitis were measured based on gingival index, plaque index, clinical attachment level, Decayed Missing Filled index and oral hygiene index-simplified. Disease activity was assessed according to Diseases Activity Score-28. Blood samples were taken to evaluate the level of anti-CCP, RF, ESR, CRP, and CBC. Data were analyzed by t-test and chi-square.<br>
<span style="color:#0000ff;"><strong><em>Results:</em></strong> </span>RA patients are more susceptible to periodontitis, plaque formation and dental caries. There is a relationship among RA disease and periodontitis, oral hygiene, gingivitis. There is also a reverse relationship between RF level and periodontitis severity likewise dental caries. There is no significant relationship between other laboratory findings and the oral status of patients.<br>
<span style="color:#0000ff;"><strong><em>Conclusion:</em></strong></span> This is more likely for RA patients to experience periodontitis which can destruct alveoli bone and it can also cause early tooth loss. Regular examination and early treatment are highly recommended.</span></span>
Rheumatoid arthritis, laboratories, mouth diseases, Disease activity score
22
28
http://caspjim.com/browse.php?a_code=A-10-1436-2&slc_lang=en&sid=1
Simin
Almasi
almasi.s@iums.ac.ir
100319475328460027304
100319475328460027304
No
Department of Romatology, Firoozgar Hospital, Rheumatology Research Center, Iran University of Medical Sciences,Tehran Iran
Mahnaz
Karbalaei sabbagh
karbalaei_mahnaz@yahoo.com
100319475328460027305
100319475328460027305
No
Department of Internal Medicine, Firoozgar Hospital Research Center, Iran University of Medical Sciences,Tehran Iran
Dorsa
Barzi
dorsabarzi@yahoo.com
100319475328460027306
100319475328460027306
No
Faculty of Veterinary Medicine, Tehran University of Medical Sciences,Tehran Iran
Azadeh
Tahooni
tahooni.a@iums.ac.ir
100319475328460027307
100319475328460027307
No
Department of Internal Medicine, Firoozgar Hospital Research Center, Iran University of Medical Sciences,Tehran Iran
Hosein
Atyabi
hosseinatiabi@yahoo.com
100319475328460027308
100319475328460027308
No
Dentist, Firoozgar Hospital Research Center, Iran University of Medical Sciences,Tehran, Iran
Samira
Basir Shabestari
samira_bsh2@yahoo.com
100319475328460027309
100319475328460027309
Yes
Department of Oral Medicine, School of dentistry, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran