en pharmacology pharmacology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><em><strong>Background:</strong></em></span> Poisoning is a major public health problem that constitutes a significant share of the global burden of disease. Previous studies conducted in this area indicated the importance of such epidemiological studies. The most critical impact of these studies is their effect on changing current regulations and, therefore, decreasing poisoning cases. We aimed to evaluate all poisoning cases with regard to the patients&rsquo; demographics and the involved intoxicants.<br> <span style="color:#0000ff;"><em><strong>Methods:</strong></em></span> The present study was conducted to investigate all poisoning cases who were admitted during a three-year period. Causes of poisoning, hospitalization, management procedures and outcome of the cases were surveyed. &nbsp;A total of 1448 patients referred to Shahid Beheshti Hospital (Babol, Iran) from 2015 to 2018.<br> <span style="color:#0000ff;"><em><strong>Results:</strong></em></span> More than half of the patients were females (51.7%), and the majority of poisoning cases were seen in patients aged between 15 to 25 years (34.2%). It was found that suicide made a large part of poisoning cases (65.6%), and females tend to attempt suicide more than males (64.3% <em>vs</em>. 35.7%, respectively). Also, regular drugs followed by club drugs were the most abundant toxic agents (52.1% and 23.3%, respectively). Aluminum phosphide (AlP) was the most lethal intoxicant in our study, accounting for 68.2% of all deaths.<br> <span style="color:#0000ff;"><em><strong>Conclusions:</strong></em></span> According to the results, it is concluded that the existing regulations for drug control and suicide prevention have not been efficient enough and further actions yet to be made to reduce the consequences of drug- and non-drug-related toxicities.</span></span> Toxicity profile, Acute poisoning, Intoxication, Babol, Aluminum phosphide, Suicide 35 44 http://caspjim.com/browse.php?a_code=A-10-108-6&slc_lang=en&sid=1 Mohammad Barary m1377b@mubabol.ac.ir 100319475328460028694 100319475328460028694 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Marzieh Pirzadeh marzieh_7676@yahoo.com 100319475328460028695 100319475328460028695 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Nastaran Rezaeian m1377b@live.com 100319475328460028696 100319475328460028696 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Mahsa Dadashnia m1377b@hotmail.com 100319475328460028697 100319475328460028697 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Sara Mohammadi-Daniali m1377b@yahoo.com 100319475328460028698 100319475328460028698 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Fatemeh Pahlavani m1377b@msn.com 100319475328460028699 100319475328460028699 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Aliasghar Manouchehri a.manoochehri@mubabol.ac.ir 100319475328460028700 100319475328460028700 No Department of Internal Medicine, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran Sohrab Kazemi kazemi.msm@gmail.com 100319475328460028701 100319475328460028701 No Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Aliakbar Moghadamnia aliamoghadamnia@gmail.com 100319475328460028702 100319475328460028702 Yes Department of Pharmacology and Toxicology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran