en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0033ff;"><strong><em>Background:</em></strong></span> Psoriasis is a chronic inflammatory disease affecting many organs. Recent studies have demonstrated that psoriasis is associated with cardiovascular disorders. We investigated the echocardiographic and conduction system changes in psoriasis patients.<br> <span style="color:#0033ff;"><strong><em>Methods:</em></strong> </span>In this case-control study, 36 psoriatic patients and 36 healthy controls were enrolled. Demographic and clinical data, echocardiographic and P wave dispersion (PWD) in 12-lead electrocardiogram were evaluated in both groups. We recruited patients with confirmed diagnosis via biopsy and have not been under recent systemic treatment. Patients with underlying cardiovascular disease were excluded from the study.<br> <span style="color:#0033ff;"><strong><em>Results:</em></strong></span> Mean age was 41.56&plusmn;16.20 and 39.67&plusmn;13.85 year in case and control groups, respectively. There was no significant difference in the baseline characteristics of the two groups. PWD was significantly higher in the case group (p<0.05). High pulmonary artery pressure was observed in 14 psoriatic patients and 1 individual in the control group (p<0.001). Left ventricular diastolic dysfunction was significantly higher among individuals who were above 60 years of age (p<0.01) but not significantly different between the two groups.<br> <span style="color:#0033ff;"><strong><em>Conclusion:</em></strong></span> Psoriatic patients are more susceptible to future development of atrial fibrillation because of higher PWD. There is no significant difference between the diastolic function in these patients.</span></span> Psoriasis, P wave dispersion, diastolic function, systolic function, pulmonary artery pressure 162 166 http://caspjim.com/browse.php?a_code=A-10-226-4&slc_lang=en&sid=1 Zeynab Aryanian z_aryanian@yahoo.com 100319475328460028154 100319475328460028154 No Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran Iraj Jafaripour iraj595@yahoo.com 100319475328460028155 100319475328460028155 No Department of Cardiology, Babol University of Medical Sciences, Babol, Iran Edris Kouhneshin edy_k_88@yahoo.com 100319475328460028156 100319475328460028156 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Roghayeh Pourkia dr.pourkia@yahoo.com 100319475328460028157 100319475328460028157 No Department of Cardiology, Babol University of Medical Sciences, Babol, Iran Mohammad Taghi Hedayati Goudarzi drmohammad.hedayati@yahoo.com 100319475328460028158 100319475328460028158 No Department of Cardiology, Babol University of Medical Sciences, Babol, Iran Soudabeh Tirgar Tabari stirgartabari@yahoo.com 100319475328460028159 100319475328460028159 No Department of Dermatology, Babol University of Medical Sciences, Babol, Iran Azar Shirzadian Kebria shirzadiank@gmail.com 100319475328460028160 100319475328460028160 No Department of Dermatology, Babol University of Medical Sciences, Babol, Iran Farbod Zahedi Tajrishi farbodzt@gmail.com 100319475328460028161 100319475328460028161 No Student Research Center, School of Medicine, Babol University of Medical Sciences, Babol, Iran Mohammad Mostafa Ansari Ramandi dr.mm.ansari@gmail.com 100319475328460028162 100319475328460028162 Yes Cardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran