Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1399
10
1
gregorian
2021
1
1
12
1
online
1
fulltext
en
Predicting new silent cerebral infarction after intracerebral hemorrhage using serum white blood cell count
Neurology
Neurology
Original Article
Original Article
<p><span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="color:#0000ff;"><strong><em>Background</em></strong><em>:</em></span> It has been confirmed that incidental silent cerebral infarctions (SCIs) found in healthy people may be risk factors for cerebrovascular diseases such as strokes and vascular dementia. The prospective study aimed to determine the utility of baseline serum white blood cell (WBC) counts to predict the emergence of new SCI after intracranial hemorrhage (ICH).<br>
<span style="color:#0000ff;"><strong><em>Methods</em></strong><em>:</em></span> This is a prospective study. From January 2016 to December 2017, we recruited 171 patients admitted to the neurology department of the Affiliated Shuyang Hospital of Xuzhou Medical University with a first episode of ICH. Serum WBC count was measured on admission. SCI was detected by cranial magnetic resonance imaging (MRI) 14 days after the onset of the ICH. Receiver operating characteristic curve analysis was used to calculate the most appropriate cut-off values of the WBC count for differentiating patients with and without SCI at the end of the study period.<br>
<span style="color:#0000ff;"><strong><em>Results</em></strong><em>:</em></span> New SCIs were detected in 28.07% of patients by cranial MRI. Multivariate logistic regression analysis showed that cerebral microbleeds (CMBs), raised WBC counts, and leukoaraiosis were independent risk factors for SCI. The most appropriate cut-off WBC count differentiating the two groups was 7.65×10<sup>9</sup>/L (sensitivity: 77.08%, specificity: 63.41%).<br>
<span style="color:#0000ff;"><strong><em>Conclusion</em></strong><em>:</em></span> Elevated levels of serum WBC counts in patients with ICH are associated with SCI. There is potential value in using serum WBC counts to predict new SCI after an acute hemorrhagic stroke.</span></span></p>
Cerebral infarction, Intracerebral Haemorrhage,WBC Count,cerebral microbleed,silent cerebral infarction.
97
102
http://caspjim.com/browse.php?a_code=A-10-1825-1&slc_lang=en&sid=1
Yuanwei
wang
wyweilmn@126.com
100319475328460027371
100319475328460027371
Yes
Department of Neurology, The Affiliated Shuyang Hospital of Xuzhou Medical University, Shuyang, Jiangsu, China