en Pulmonology Pulmonology case report case report <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><span new="" roman="" times=""><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Goodpasture syndrome (GPS) rarely affects parturients which may quickly result in severe pulmonary and renal damage with significant fetomaternal morbidity.<span style="font-size:9.0pt"></span></span></span><br> <span style="line-height:14pt"><span new="" roman="" times=""><b><i><span style="color:blue">Case Presentation</span></i></b><i><span style="color:blue">:</span></i> A 35-year-old white multiparous lady, presented with acute progressive respiratory failure at 32^th gestational age. She had fever, cough, severe dyspnea and lately hemoptysis and severe hypoxia with bilateral alveolar opacity in chest imaging, with no response to broad spectrum antibiotic. GPS diagnosis was confirmed by high anti- glomerular basement membrane (anti GBM) titer, without the similar history in the past parities. High dose intravenous methylprednisolone ended to dramatic clinical response. She was maintained on glucocorticoids for five weeks before the successful delivery of a live healthy fetus at 39 Weeks.</span></span></span></span><span style="font-size:12pt"><span style="line-height:14pt"><span new="" roman="" style="font-family:" times=""><i><span style="font-size:10.0pt"></span></i></span></span></span><br> <span style="font-size:12pt"><span style="line-height:14pt"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:10.0pt"><span style="color:blue">Conclusion</span></span></i></b><i><span style="font-size:10.0pt"><span style="color:blue">:</span></span></i> <span style="font-size:10.0pt">This study demonstrated a successful pregnancy outcome which was achieved in the present GPS parturient with a careful antepartum care involving maternal-fetal status by serial pulmonary, renal monitoring and special treatment of disease.</span><b><i><span style="font-size:10.0pt"><span style="color:#0033cc"></span></span></i></b></span></span></span> Goodpasture's syndrome, Pregnancy, Respiratory failure, Renal involvement, Case report. 442 446 http://caspjim.com/browse.php?a_code=A-10-2023-1&slc_lang=en&sid=1 Taghi Riahi riahidt@yahoo.com 100319475328460036373 100319475328460036373 No Hazrate Rasool hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran Laily Najafi lailynajafi@yahoo.com 100319475328460036374 100319475328460036374 No Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran Omolbanin Asadi Ghadikolaei oasady@gmail.com 100319475328460036375 100319475328460036375 No Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran. Mohammad Hadi Tajik Jalayeri drtajikinternist@gmail.com 100319475328460036376 100319475328460036376 Yes Masih Daneshvari hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran