en Cardiology Cardiology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Ventricular repolarization measurement by QTc interval and QT dispersion can recognize high-risk patients. Previous research tended to evaluate the act of repolarization indicators alone but this study aimed to elucidate their prognostic utility before and after modifying confounding parameters in risk stratification of different aspects of prognosis in decompensated heart failure patients with systolic dysfunction.<span style="font-size:9.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> Data of 98 variables were evaluated to determine their predictive value concerning arrhythmic events, in-hospital, and long-term mortality.<i><span style="font-size:10.0pt"></span></i></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> From 858 cases that presented with acute heart failure, 19.2% (n=165) were enrolled in the study. During hospitalization, arrhythmic events and cardiac-related mortality occurred in 56(33.9%) and 11(7%) patients, respectively. QTc and QT dispersion were independent predictors of arrhythmia and in-hospital mortality after adjustment of the variables (arrhythmic events: QTc interval OR 1.085, P=0.007, QT dispersion OR 1.077, P=0.007, in-hospital mortality: QTc interval OR 1.116, P=0.009, QT dispersion OR 1.067, P=0.011). After being discharged, they were tracked for 181 &plusmn; 56 days. Within the 16 deaths in follow-up time, 6 sudden cardiac deaths were documented. Cox regression, defined QTc as the predictor of all-cause and sudden death mortality (all-cause: HR 1.041, 95% CI 1.015-1.067, P=0.002; sudden death: HR 1.063, 95% CI 1.023-1.105, P=0.002); nevertheless, efforts to demonstrate QT dispersion as the predictor failed.<b><i><span style="color:blue"></span></i></b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> The predictive nature of QT parameters was significant after modification of the variables; therefore, they should be measured for risk stratification of ventricular repolarization arrhythmia and death in decompensated heart failure patients.</span></span></span> Prognostic value, QT parameters, Decompensated heart failure, ventricular systolic dysfunction 533 545 http://caspjim.com/browse.php?a_code=A-10-2240-1&slc_lang=en&sid=1 Mohammad Reza Hatamnejad mhatamnejad7@gmail.com 100319475328460037553 100319475328460037553 No Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Hamed Bazrafshan hamedbazrafshan@yahoo.com 100319475328460037554 100319475328460037554 Yes Department of Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran Morteza Hosseinpour Third.pace@gmail.com 100319475328460037555 100319475328460037555 No Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Peyman Izad Panah Paymanizadpanah@gmail.com 100319475328460037556 100319475328460037556 No Department of Cardiology, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad Reza Kasravi Mrkasravi@gmail.com 100319475328460037557 100319475328460037557 No Faculty of Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran Mehdi Bazrafshan Mehdi.bazrafshan9695@gmail.com 100319475328460037558 100319475328460037558 No Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran