Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1394
10
1
gregorian
2016
1
1
7
1
online
1
fulltext
en
Difficulties in the diagnosis and management of alveolar hydatid disease: A case series
Internal
Internal
Case Series
Case Series
<p dir="ltr" style="text-align: justify"><span style="font-family: times new roman"><span style="color: rgb(0, 0, 255)"><strong><em>Background: </em></strong></span>Alveolar echinococcosis (AE) is a chronic, rare and sometimes lethal parasitic infection in humans, caused by the larval stage of the fox tapeworm Echinococcus multilocularis. This study aimed to investigate the clinical aspects and treatment outcomes of patients with alveolar hydatid disease.</span></p>
<p dir="ltr" style="text-align: justify"><span style="font-family: times new roman"><span style="color: rgb(0, 0, 255)"><strong><em>Methods:</em></strong></span> The medical records of patients with alveolar echinococcosis admitted between 1997 and 2012 were reviewed. Diagnosis was confirmed by physical examination, ultrasonography and CT scanning and MRI. Various treatment techniques were used such as complete liver resection in seven (38.89%) patients, biliary bypass in two (11.11%) patients, laparotomy and tumor biopsy in eight (44.44%) patients and long term medical treatment in one (5.56%) patient. After discharge, all patients were followed to determine the effect of treatment, complications, recurrences and survival.</span></p>
<p dir="ltr" style="text-align: justify"><span style="font-family: times new roman"><span style="color: rgb(0, 0, 255)"><strong><em>Results:</em></strong></span> A total of 18 patients with mean age of 46.11±15.14 years (range 23-74 years) were studied. The disease was more prevalent in women than men (78.9% vs 4, 21.1%, P=0.021). Fourteen (77.78%) patients live in Chenaran, a town located in Khorasan, Iran). Death occurred in (22.22%) patients after an average period of 45.70±7.50 months after disease onset. 14 remaining patients survived after a mean follow-up duration of 54.60±29.17 months.</span></p>
<p dir="ltr" style="text-align: justify"><span style="font-family: times new roman"><span style="color: rgb(0, 0, 255)"><strong><em>Conclusion:</em></strong></span> Diagnosis of alveolar echinococcosis should be considered in endemic area. Early diagnosis and treatment is associated with excellent outcome.</span></p>
Alveolar echinoccosis, Echinococcus multilocularis, Diagnosis, Treatment
52
56
http://caspjim.com/browse.php?a_code=A-10-128-1&slc_lang=en&sid=1
Ghodratollah
Maddah
MaddahGh@mums.ac.ir
10031947532846004688
10031947532846004688
Yes
Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abbas
Abdollahi
AbdollahiA@mums.ac.ir
10031947532846004689
10031947532846004689
No
Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Reza
Sharifi Nooghabi
SharifiR881@mums.ac.ir
10031947532846004690
10031947532846004690
No
Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza
Tavassoli
TavassoliA@mums.ac.ir
10031947532846004691
10031947532846004691
No
Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Taghi
Rajabi Mashhadi
RajabiMT@mums.ac.ir
10031947532846004692
10031947532846004692
No
Endoscopic and Minimally Invasive Surgery Research Center, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Azadeh
Jabbari Nooghabi
JabbariA891@mums.ac.ir
10031947532846004693
10031947532846004693
No
Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mehdi
Jabbari Nooghabi
JabbariNM@yahoo.com
10031947532846004694
10031947532846004694
No
a: Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. b: Department of Statistics, Faculty of Mathematical Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.