Caspian Journal of Internal Medicine

en The association between Antihypertensive drugs and oral health- related quality of life in the elderly: results of Amirkola cohort study Dentistry Dentistry Original Article Original Article <pre> Background: Hypertension is one of the most common chronic diseases in the world. The prevalence of hypertension in the elderly is increasing. Patients with high blood pressure have to take medication throughout their lives. In this study, the relationship between antihypertensive drugs and oral health-related quality of life in the elderly was evaluated. Methods: This modified cross-sectional study, which is the part of the second phase of the Amirkola Health and Ageing Project (AHAP), was performed on 900 elderly people. Participants included 300 people with hypertension under medical treatment, 300 people with hypertension without medication and 300 people with normal blood pressure. All patients’ blood pressure was recorded, and the standard xerostomia questionnaire and GOHAI questionnaire (Geriatric Oral Health Assessment Index) was completed for all participants. Then, the obtained data were analyzed by SPSS 17, whereby student’s t-test, ANOVA and chi square, Pearson correlation coefficient and logistic regression model were used. A p<0.05 was considered statistically significant. Results: The mean GOHAI score in the three studied groups: hypertensive under medication treatment, hypertensive without medication treatment and normal blood pressure (51.1±7.4, 51.7±7.3, 51.1±7.5, respectively) did not differ significantly (P=0.533).The frequency of xerostomia was significantly different in the three groups (P=0.008). Among the antihypertensive drugs, the highest rate of xerostomia was due to the use of calcium channel blockers (31.1%) and diuretics (26.8%). Conclusion: In our study, although antihypertensive medications were associated with xerostomia, they did not decrease the oral health-related quality of life. </pre> quality of life, xerostomia, elderly, anti hypertensive drugs 582 588 http://caspjim.com/browse.php?a_code=A-10-772-2&slc_lang=en&sid=1 Seyyedeh Fatemeh Langari s.fatemeh.l@gmail.com 100319475328460037577 100319475328460037577 No Student Research Committee, school of dentistry, Babol University of Medical Sciences, Babol,Iran Seyed Reza Hosseini hosseinim46@yahoo.com 100319475328460037578 100319475328460037578 No Social Determinants of Health Research Centre, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. Ali Bijani alibijani@yahoo.com 100319475328460037579 100319475328460037579 No Social Determinants of Health Research Centre, Health Research Institute. Babol University of Medical Sciences,Babol, Iran. Niloofar Jenabian njenabian@hotmail.com 100319475328460037580 100319475328460037580 No Department of Periodontics, Oral Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran. Mina Motalebnejad m.motalebnejad@yahoo.com 100319475328460037581 100319475328460037581 No Department of Oral and Maxillofacial Medicine, Oral Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Elham Mahmoodi mahmoudi86@yahoo.com 100319475328460037582 100319475328460037582 No Department of Endodontics, Dental Materials Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran Zahra Sadat Madani madani_z@yahoo.com 100319475328460037583 100319475328460037583 No Department of Endodontics, Dental Materials Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. Fatemeh Sayadi f.sayyadi90@yahoo.com 100319475328460037584 100319475328460037584 No Department of Oral and Maxillofacial Medicine, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran MohammadMehdi Naghibi Sistani m.naghibi@mubabol.ac.ir 100319475328460037585 100319475328460037585 No Department of Community Oral Health, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. Reza Ghadimi rezaghadimi@yahoo.com 100319475328460037586 100319475328460037586 No Social Determinants of Health Research Centre, Health Research Institute. Babol University of Medical Sciences, Babol, Iran Fateme Baladi Mahya_baladi@gmail.com 100319475328460037587 100319475328460037587 No Department of oral and maxillofacial medicine, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. Mohammad Hajimirzamohammad haji58@yahoo.com 100319475328460037588 100319475328460037588 No Department of oral and maxillofacial medicine, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran Mahsa Mehryari mah.mehryari@yahoo.com 100319475328460037589 100319475328460037589 No Department of oral and maxillofacial medicine, Dental Materials Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran. Atena Shirzad ats60dent@gmail.com 100319475328460037590 100319475328460037590 Yes Department of oral and maxillofacial medicine, Oral Health Research Center, Health Research Institute. Babol University of Medical Sciences, Babol, Iran.