en Neurology Neurology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Patients with multiple sclerosis (MS) should have magnetic resonance imaging evaluation regularly. They will experience anxiety before this examination. We conducted this study to evaluate the validity and reliability of emotions and attitudes towards MRI&rdquo; (MRI-EMA).</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b>&nbsp;One hundred-nine patients&nbsp;with MS were asked to fill the valid and reliable Persian version of Beck Anxiety Inventory (BAI), and MRI-EMA, questionnaires. Two weeks later, twenty cases were asked to fill the questionnaire again to assess reliability. The intra-class correlation coefficient (ICC) and Cronbach&#39;s alpha analysis were used. The correlation coefficient between BAI and MRI-EMA was calculated. Five neurologists assessed content validity by content validity ratio (CVR) and content validity index (CVI).<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> The mean age was 37.2&plusmn;1.2 years and 77% were females. CVI and CVR for all questions were 100%. The correlation coefficient between BAI and MRI-EMA was r=0.1, P=0.1 and only fear of MRI subscale was significantly correlated with BAI. The ICC of all questions was between 0.79 and 0.98.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Patients with MS have to be routinely screened with MRI which provides anxiety for them. Considering MRI related anxiety is crucial for these cases. The Persian version of the MRI-EMA questionnaire is a valid and reliable instrument for measuring MRI related anxiety in patients with multiple sclerosis.<span style="font-size:10.0pt"></span></span></span></span><br> <br> <span dir="LTR"></span> multiple sclerosis, magnetic resonance imaging, anxiety. 449 453 http://caspjim.com/browse.php?a_code=A-10-2449-3&slc_lang=en&sid=1 Abdorreza Naser Moghadasi abdorrezamoghadasi@gmail.com 100319475328460042986 100319475328460042986 No Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Sara Hamtaei Gashti Sarah.Hamtaee@yahoo.com 100319475328460042987 100319475328460042987 No Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Mohammad Ali Sahraian msahrai@tums.ac.ir 100319475328460042988 100319475328460042988 No Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Mahsa Ghajarzadeh m.ghajarzadeh@gmail.com 100319475328460042989 100319475328460042989 Yes Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran