Caspian Journal of Internal Medicine
1
Caspian J Intern Med
Medical Sciences
http://caspjim.com
1
admin
2008-6164
2008-6172
8
10.22088/cjim
14
8888
13
en
jalali
1401
12
1
gregorian
2023
3
1
14
2
online
1
fulltext
en
Trigeminal neuralgia: IncobotulinumtoxinA (Xeomin), can it decrease the pharmacological intervention? (A case series)
Neurology
Neurology
Case Series
Case Series
<span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Trigeminal neuralgia is one of the most disabling facial pain syndromes. In recent years' new therapeutic strategy, incobotulinumtoxin A has emerged. The aim of the current study was to determine the time and duration of pain in 3 cases with pharmacological treatment and incobotulinumtoxin A.<span style="font-size:9.0pt"></span></span><br>
<span style="line-height:14pt"><b><i><span style="color:blue">Case presentation: </span></i></b>In three patients with different onsets, trigeminal neuralgia was diagnosed. Pain severity was assessed by the visual analogue scale. Patient demographics and clinical data were filled in a checklist. They were females with age ranging from 39 to 49 years. Two patients had normal MRI and one patient had no any recent MRI. One center and specialist injection Xeomin 50 units for one time. Despite long time oral treatment, their symptoms had no significant improvement, but after incobotulinumtoxin A injection, pain frequency, severity and duration decreased in patients<b><i><span style="color:blue">.</span><span style="color:blue"></span></i></b></span><br>
<span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Result showed that the frequency, severity and duration of pain attacks was efficiently decreased by incobotulinumtoxin A with low side-effects. Its complication and side-effect should be considered in the future.<b><i><span style="color:#0033cc"></span></i></b></span></span></span>
Trigeminal, Neuralgia, Pain, Iran.
376
379
http://caspjim.com/browse.php?a_code=A-10-1466-9&slc_lang=en&sid=1
Meghdad
Hosseini
mubmeghdad271@gmail.com
100319475328460041903
100319475328460041903
No
Department of Neurology, Shahid Beheshti University of Medical Science, Tehran, Iran
Farhad
Asarzadegan
alijanpour.sh@live.com
100319475328460041904
100319475328460041904
Yes
Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Erfan
Shafiee
alijanpour.sh@live.com
100319475328460041905
100319475328460041905
No
Department of Neurology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shayan
Alijanpour
sh.alijanpour@mubabol.ac.ir
100319475328460041906
100319475328460041906
No
Student Research Committee, Faculty of Nursing and midwifery, Tehran University of Medical Science, Tehran, Iran