en Dermathology Dermathology case report case report <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="unicode-bidi:embed"><span style="line-height:107%"><em><span style="color:#0000ff;"><b><span style="line-height:107%"><span new="" roman="" times="">Background:</span></span></b></span></em><span style="line-height:107%"><span new="" roman="" times=""> Focal epithelial hyperplasia (FEH) or Heck&#39;s disease is a condition of the oral mucosa defined by the asymptomatic presence of papules or nodules distributed in the oral mucosa, gingiva, tongue and lips. Heck&#39;s disease is most reported in the Native American and South African populations. It is mainly found in children with confirmed human papillomavirus (HPV) mostly HPV13 and 32. We report a rare case of Heck&#39;s disease in an Iranian-Turkmen girl with HPV6.</span></span></span></span><br> <span style="unicode-bidi:embed"><span style="line-height:107%"><b><span style="line-height:107%"><span new="" roman="" times=""><span style="color:#0000ff;"><em>Case presentation:</em></span> </span></span></b><span style="line-height:107%"><span new="" roman="" times="">A 9-year-old Turkmen girl had esthetic and traumatic chief complaints caused by some enlarged lesions on her lips during the last six months. The patient did not have any systemic disease. Oral manifestations were white and pink nodules and papules on lips, buccal mucosa, and palate. Her mother had less than 10 similar lesions on her tongue and floor of the mouth that resolved, and only was papule was remained. HPV 6 was confirmed.</span></span></span></span><br> <span style="unicode-bidi:embed"><span style="line-height:107%"><b><span style="line-height:107%"><span new="" roman="" times=""><em><span style="color:#0000ff;">Conclusion:</span></em> </span></span></b><span style="line-height:107%"><span new="" roman="" times="">Patients with Heck&#39;s disease may be referred to an oral specialist, dermatologist, or otolaryngologist<b>, </b>so there should be enough knowledge about this condition among clinicians.</span></span></span></span><br> &nbsp;</span></span> Heck's disease, focal epithelial hyperplasia, Human papillomavirus, HPV6, Oral mucosa, Case report 0 0 http://caspjim.com/browse.php?a_code=A-10-2703-1&slc_lang=en&sid=1 Sudabeh Baghery Moghadam dr.baqerymoqadam@gmail.com 100319475328460042154 100319475328460042154 No Dental Research Center, Golestan University of Medical Sciences, Gorgan, Iran Fatemeh Mirzaei fatemehmirzaei.ir.1998@gmail.com 100319475328460042155 100319475328460042155 No Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran Shohreh Ghasemi SGHASEMI@augusta.edu 100319475328460042156 100319475328460042156 Yes Department of Oral and Maxillofacial surgery, The Dental College of Georgia at Augusta University, Augusta, Ga