en Orthopedy Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Tennis elbow or lateral epicondylitis is a common complaint involving about a 3-5% cases in a community. Non-surgical treatment is effective in 80% of cases. Recent studies have shown the effect of autologous blood on improving the pain and function of affected patients. The present study aimed to compare the effectiveness of steroid and autologous blood local injection in controlling pain and disability in the short and long term.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> The present study was a clinical trial conducted in Shahid Beheshti Hospital of Babol. A total of 60 patients were divided into 3 groups; A group injected at the site of lateral epicondylitis with steroid (methylprednisolone acetate-40mg) and another group with autologous blood (2ml of venous blood), and the other group used a brace for 3 weeks. Patients were followed-up for 15, 30, and 90 days, and the PRTEE assessment questionnaire assessed their pain and disability.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> On the 15th day, there was no statistically significant difference in pain and function in the three groups, although the injectable groups were relatively more effective. On the 30th day, the local corticosteroid was significantly better than the autologous blood group, while on the 90th day, autologous blood was significantly better than the local corticosteroid. The average day, in which 25% improvement was gained, was lower in the autologous blood transfusion group.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Regarding the long-term effect of autologous blood on corticosteroid injections, it was recommended as a lateral epicondylitis treatment.<span style="font-size:10.0pt"></span></span></span></span><br> &nbsp; Tennis elbow, Lateral epicondylitis, autologous blood, Corticosteroid, Brace 633 639 http://caspjim.com/browse.php?a_code=A-10-2120-1&slc_lang=en&sid=1 Rahmatollah Jokar m1377b@gmail.com 100319475328460044870 100319475328460044870 Yes Department of Orthopedic Surgery, School of Medicine, Babol University of Medical Sciences, Babol, Iran Seyyed Mokhtar Esmaeilnejadganji smsnganji@yahoo.com 100319475328460044871 100319475328460044871 No Department of Orthopedic Surgery, School of Medicine, Babol University of Medical Sciences, Babol, Iran Ali Bijani alibijani@yahoo.com 100319475328460044872 100319475328460044872 No Babol University of Medical Sciences, Babol, Iran Sekineh kamali Ahangar bcrdc90@yahoo.com 100319475328460044873 100319475328460044873 No Clinical Research Development Center, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran Raheleh Javer m1377b@live.com 100319475328460044874 100319475328460044874 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Ghazal Mohammadi m1377b@hotmail.com 100319475328460044875 100319475328460044875 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran