en pharmacology pharmacology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background:</span></i></b> Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam.<span style="font-size:9.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digoxin, and dronabinol poisoning referred to the toxicology laboratory of Ilam University of Medical Sciences were analyzed using the HPLC method, and the results were analysed using SPSS software.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> Results showed that the percentage of drug use is greater in men than in women. The highest percentage of morphine and methadone poisonings were detected in those under the age of 40, whereas the highest percentage of digoxin poisonings were recorded in those over the age of 80. As a result, the average age of digoxin users was substantially greater in men than in women. Methadone consumers showed significantly greater blood levels than others. In addition, there was a significant difference (P<0.01) in blood levels between men and women who used morphine.<b><i><span style="color:blue"></span></i></b></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion:</span></i></b> In general, it is important to understand the status of drug poisoning with drugs such as morphine, methadone, digoxin, and dronabinol, as well as the prognosis associated with the treatment process of such poisoning.<b><i><span style="color:#0033cc"></span></i></b></span></span></span><br> &nbsp; Poisoning drug, Dronabinol, Digoxin, Methadone, Morphine 356 364 http://caspjim.com/browse.php?a_code=A-10-2255-3&slc_lang=en&sid=1 Kourosh Saki saki.k@ymail.com 100319475328460041882 100319475328460041882 No Department of Psychiatry, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mahmoud Bahmani pharmabiology2021@gmail.com 100319475328460041883 100319475328460041883 No Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran Golnaz Zamanian gzamanian@ymail.com 100319475328460041884 100319475328460041884 No Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran Naser Abbasi ilamfarma@gmail.com 100319475328460041885 100319475328460041885 No Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran Ali Aidy aliaidy@ymail.com 100319475328460041886 100319475328460041886 No Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran Aliasghar Manouchehri mahmood.bahmani@gmail.com 100319475328460041887 100319475328460041887 Yes Department of Internal Medicine, Shahid Beheshti Hospital, Babol University of Medical Sciences, Babol, Iran Sudip Kumar Mandal gotosudip79@gmail.com 100319475328460041888 100319475328460041888 No B.C. Roy College of Pharmacy and Allied Health Sciences, Meghnad Saha Sarani, Bidhan Nagar, Durgapur-713206, West Bengal, India Paramita Ganguly proyganguly1@gmail.com 100319475328460041889 100319475328460041889 No Department of Pharmaceutical Technology, Brainware University, 398-Ramkrishnapur Road, Barasat, Kolkata-700125, West Bengal, India Samira Shokri Shokrisamira22@yahoo.com 100319475328460041890 100319475328460041890 No Department of Environmental Health Engineering, Division of Food Safety & Hygiene, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran