en Neurology Neurology Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Possible association between minerals contributing and mortality related to stroke were seen, but prospective data on the relation of vitamin D, magnesium and calcium serum levels with stroke were inconsistent. Consideration about the potential health effects of minerals and nutrients, the current study was conducted.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Methods:</span></i></b> This analytical cross-sectional study was conducted on 216 stroke survivors who were referred to the Ayatollah Rouhani Hospital of Babol, Iran. Demographic characteristics, clinical variables, and serum mineral levels were completed in the checklist. Admit score and discharge scale of these patients were determined according to the National Institute of Health Stroke Scale. A path model was constructed to explore the interrelationship between variables and to verify the relationship between variables and disability discharges.<span style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> Of 216 stroke patients, 185 (85.6%) cases were ischemic. The discharge status of 29 (12.9%) cases were severe or expired. The patients with moderate and severe admit scores, hemorrhagic stroke type, diabetes mellitus, hypertension and live in the village significantly had a poor discharge disability scale (all of p<0.05). Of all direct paths, Mg (&beta;=-2.85), and among indirect paths, calcium(&beta;=-3.59) had the highest effect on the discharge scale. Only mg had affected the discharge scale through direct and indirect (&beta;=-2.45) paths and had the greatest reverse effect on the discharge scale (&beta;=-5.30; totally).<span dir="RTL" lang="FA"><span style="color:red"></span></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> Hypomagnesemia and hypocalcemia play a mediatory role in poor outcomes. Especially, hypomagnesemia was the direct parameter for poor outcomes. The independent role of each mineral in this issue is difficult to define and suggested for future study.<span style="font-size:10.0pt"></span></span></span></span><br> &nbsp; magnesium, calcium, vita D, ischemic stroke, stroke 124 131 http://caspjim.com/browse.php?a_code=A-10-1466-10&slc_lang=en&sid=1 Soraya Khafri Khafri@yahoo.com 100319475328460046544 100319475328460046544 No Assistant Professor of Biostatic, Department of Biostatistics and Epidemiology, Babol University of Medical Sciences, Babol, Iran Alijan Ahmadi Ahangar sepanta1968@yahoo.com 100319475328460046545 100319475328460046545 No Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Payam Saadat Sepanta1968@yahoo.com 100319475328460046546 100319475328460046546 Yes Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Shayan Alijanpour sh.alijanpour@mubabol.ac.ir 100319475328460046547 100319475328460046547 No Students Scientific Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. Mansor Babaei m.babaei@mubabol.ac.ir 100319475328460046548 100319475328460046548 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Mohammadali Bayani m.bayani@mubabol.ac.ir 100319475328460046549 100319475328460046549 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Alireza firouzjahi firouzjahi@yahoo.com 100319475328460046550 100319475328460046550 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Farshad Fadaee Jouybari FadaeeJouybari@yahoo.com 100319475328460046551 100319475328460046551 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Sepideh Hosseini Shirvani HosseiniShirvani@yahoo.com 100319475328460046552 100319475328460046552 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Zahra Frajzadeh Frajzadeh@yahoo.com 100319475328460046553 100319475328460046553 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran. Nafisseh Ezamie Ezamie@yahoo.com 100319475328460046554 100319475328460046554 No Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.