en Infectious Diseases Infectious Diseases Original Article Original Article <span style="font-size:14px;"><span style="font-family:Times New Roman;"><span style="line-height:14pt"><b><i><span style="color:blue">Background</span></i></b><i><span style="color:blue">:</span></i> Early diagnosis of sepsis can lead to rapid initiation of treatment and reduced mortality. The aim of this study was to investigate the relationship between eosinopenia and neutrophil-lymphocyte ratio (NLR) with sepsis-related mortality in the intensive care unit.</span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Results:</span></i></b> Out of 100 patients studied, 59 patients survived and 41 patients died and the mean age of the patients was 63.27&plusmn;16.13 years. Out of 40 patients with eosinopenia, 19(46.3%) died and out of 60 patients with normal eosinophil, 22(53.7%) died (P=0.28). The NLR on the first day in died patients was significantly higher than in the surviving patients (P=0.009). The increase in SOFA Score (p<0.001 and OR=1.49) and the increase in NLR (P=0.02 and OR=3.38) has a direct relationship with the mortality rate. <span lang="FA" dir="RTL" style="font-size:10.0pt"></span></span><br> <span style="line-height:14pt"><b><i><span style="color:blue">Conclusion</span></i></b><i><span style="color:blue">:</span></i> The results of the present study in sepsis patients showed that patients who had a higher neutrophil-to-lymphocyte ratio had higher mortality and there was no relationship between eosinopenia and mortality rate.</span></span></span><br> &nbsp; Mortality, Sepsis, Eosinophils, Lymphocytes, Neutrophils 444 450 http://caspjim.com/browse.php?a_code=A-10-2120-2&slc_lang=en&sid=1 Parviz Amri pamrimaleh@yahoo.com 100319475328460053282 100319475328460053282 No Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Armin Nejadnaderi Armin.nejadnaderi@gmail.com 100319475328460053283 0009-0003-4745-0981 No Student Research Committee, Babol University of Medical Sciences, Babol, Iran Hemmat Gholinia h_gholinia@yahoo.com 100319475328460053284 100319475328460053284 No Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Fatemeh Heidarnia f.heidarnia4@gmail.com 100319475328460053285 0009-0004-6290-4133 No Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Masomeh Bayani m_baiany@yahoo.com 100319475328460053286 100319475328460053286 Yes Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran